143541-29-1

Upstream product

• 140860-79-3 4,4-difluoro-1-phenyl-3-(trifluoromethyl)but-3-en-1-one 
• 35443-84-6 4,4,4-trifluoro-1-phenyl-3-(trifluoromethyl)but-2-en-1-one 
• 140860-85-1 2-fluoro-5-phenyl-3-(trifluoromethyl)furan 
• 60-56-0 2-Mercapto-1-methylimidazole 

Relevant academic research and scientific papers

Partially fluorinated heterocycles from 4,4-bis(trifluoromethyl)-hetero-1, 3-dienes via C-F bond activation - Synthesis of 2-fluoro-3-(trifluoromethyl) furans

An efficient synthesis of 2-fluoro-3-(trifluoromethyl)furans was developed. Keystep of the reaction sequence is a [4 + 1] cycloaddition reaction of tin(II)chloride to 4,4-bis(trifluoromethyl)-1-oxabuta-1,3-dienes. At elevated temperatures the tin heterocy

Ein neues Verfahren zur positionsselektiven Einfuehrung von Trifluormethylgruppen in Heteroaromaten: Synthese von 3-Trifluormethylfuranen

Transformation of 4,4-bis(trifluoromethyl)-1-oxabuta-1,3-dienes (2) into 2-fluoro-3-trifluoromethylfurans (4) can be achieved in a two step procedure by treatment with tin(II) chloride and sodium hydride.The fluorine atom at skeleton position 2 is replace