35443-84-6

Upstream product

• 100-42-5 styrene 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 82959-21-5 3,4,4,4-Tetrafluoro-1-phenyl-3-trifluoromethyl-butan-1-one 
• 731-00-0 4,4,4-trifluoro-3-hydroxy-3-methyl-1-phenyl-3-trifluoromethylbutan-1-one 
• 684-16-2 Hexafluoroacetone 
• 20913-05-7 (Benzoylmethylene)triphenylphosphorane 
• 143211-22-7 4,4,4-Trifluoro-1-phenyl-3-trifluoromethyl-3-trimethylsilanyloxy-butan-1-one 

Downstream Products

• 140860-79-3 4,4-difluoro-1-phenyl-3-(trifluoromethyl)but-3-en-1-one 
• 219915-34-1 Ni(PMe3)2(η(2)-PhCOCHC(CF3)2) 
• 219915-29-4 Ni(η(4)-1,5-cyclooctadienyl)(η(2)-PhCOCHC(CF3)2) 
• 140860-85-1 2-fluoro-5-phenyl-3-(trifluoromethyl)furan 
• 155262-17-2 2-fluoro-5-phenyl-3-trifluoromethylthiophene 
• 143541-29-1 2-(N-methylimidazol-2-ylthio)-5-phenyl-3-(trifluoromethyl)furan 
• 143541-34-8 2,5-diphenyl-3-(trifluoromethyl)furan 
• 143541-26-8 2-ethoxy-5-phenyl-3-(trifluoromethyl)furan 

Relevant academic research and scientific papers

Cobalt-Catalyzed Hydroxyperfluoroalkylation of Alkenes with Perfluoroalkyl Bromides and Atmospheric Oxygen

A mild and efficient method for the cobalt-catalyzed hydroxyperfluoroalkylation of alkenes has been developed. This method demonstrated broad substrate scope, good yields, and mild conditions with the tolerance of mono-, di-, and trisubstituted alkenes including both styrenes and non-activated aliphatic olefins. This strategy offered a valuable solution for rapid and efficient construction of β-perfluoroalkyl alcohols using widely available and inexpensive perfluoroalkyl bromides and atmospheric oxygen.

Synthese von 4,4-Bis(trifluormethyl)-1-oxabuta-1,3-dienen

Silyl enol ethers (1) and hexafluoroacetone (2) react to give O-silylated aldol adducts 3 which, after desilylation with methanol/hydrochloric acid, are transformed into 4,4-bis(trifluoromethyl)-1-oxabuta-1,3-dienes (5) on treatment with trifluoroacetic a

REGIOSPECIFIC α-HEXAFLUOROISOPROPYLIDENATION OF KETONES USING HEXAFLUOROACETONE

Hexafluoroacetone (HFA) reacted regiospecifically with various enol silyl ethers at -30 to -35 deg C in the presence of a Lewis acid to give HFA aldols, or α-bis(trifluoromethyl)hydroxymethyl carbonyl compounds, in good yields.The reaction of HFA with die

A NEW METHOD FOR THE PREPARATION OF α-(PERFLUOROALKYL) CARBONYL AND γ-(PERFLUOROALKYL)-α,β-UNSATURATED CARBONYL COMPOUNDS

RfI(Ph)OSO2CF3 or RfI(Ph)OSO3H smoothly reacted with various trimethylsilyl enol ethers under mild conditions to give α(perfluoroalkyl) carbonyl and γ=)perfluoroalkyl)-α,β-unsaturated carbonyl compounds in high yields.