14355-04-5 Usage
General Description
N-[3-(Trifluoromethyl)benzyl]ethylamine is a chemical compound with the molecular formula C10H12F3N. It is a tertiary amine with a trifluoromethyl group attached to a benzene ring, and an ethyl group attached to the amino nitrogen. N-[3-(Trifluoromethyl)benzyl]ethylamine is used in various organic synthesis reactions and can act as a building block for the preparation of pharmaceuticals, agrochemicals, and other fine chemicals. It is also used as an intermediate in the manufacture of other compounds, such as dyes and pigments. N-[3-(Trifluoromethyl)benzyl]ethylamine is a colorless liquid with a strong and unpleasant odor, and it should be handled and stored with proper care due to its hazardous nature.
Check Digit Verification of cas no
The CAS Registry Mumber 14355-04-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,3,5 and 5 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 14355-04:
(7*1)+(6*4)+(5*3)+(4*5)+(3*5)+(2*0)+(1*4)=85
85 % 10 = 5
So 14355-04-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H12F3N/c1-2-14-7-8-4-3-5-9(6-8)10(11,12)13/h3-6,14H,2,7H2,1H3
14355-04-5Relevant articles and documents
First Nondiscriminating Translocator Protein Ligands Produced from a Carbazole Scaffold
Cheng, Hei Wun Alison,Sokias, Renee,Werry, Eryn L.,Ittner, Lars M.,Reekie, Tristan A.,Du, Jonathan,Gao, Quanqing,Hibbs, David E.,Kassiou, Michael
supporting information, p. 8235 - 8248 (2019/10/11)
Development of neuroinflammation agents targeting the translocator protein (TSPO) has been hindered by a common single nucleotide polymorphism (A147T) at which TSPO ligands commonly lose affinity. To this end, carbazole acetamide scaffolds were synthesized and structure activity relationships elaborated to explore the requirements for high-affinity binding to both TSPO wild type (WT) and the polymorphic TSPO A147T. This study reports high binding affinity and nondiscriminating TSPO ligands.
