14355-04-5 Usage
Uses
Used in Pharmaceutical Industry:
N-[3-(Trifluoromethyl)benzyl]ethylamine is utilized as a building block in the synthesis of pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique chemical structure allows it to be incorporated into various medicinal compounds, enhancing their efficacy and pharmacological properties.
Used in Agrochemical Industry:
In the agrochemical sector, N-[3-(Trifluoromethyl)benzyl]ethylamine is employed as a key component in the production of agrochemicals, such as pesticides and herbicides. Its chemical properties enable it to be integrated into formulations that target specific pests or weeds, improving the effectiveness of these products in agricultural applications.
Used in Fine Chemicals Industry:
N-[3-(Trifluoromethyl)benzyl]ethylamine is used as an intermediate in the synthesis of fine chemicals, which are high-purity chemicals used in various applications, including fragrances, flavors, and specialty chemicals. Its versatility in chemical reactions allows for the creation of a wide range of products with specific properties and applications.
Used in Dyes and Pigments Industry:
N-[3-(Trifluoromethyl)benzyl]ethylamine is also used as an intermediate in the manufacture of dyes and pigments, where its chemical structure contributes to the color and stability of these products. Its presence in dye formulations can enhance their performance in various applications, such as textiles, plastics, and printing inks.
Check Digit Verification of cas no
The CAS Registry Mumber 14355-04-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,3,5 and 5 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 14355-04:
(7*1)+(6*4)+(5*3)+(4*5)+(3*5)+(2*0)+(1*4)=85
85 % 10 = 5
So 14355-04-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H12F3N/c1-2-14-7-8-4-3-5-9(6-8)10(11,12)13/h3-6,14H,2,7H2,1H3
14355-04-5Relevant academic research and scientific papers
First Nondiscriminating Translocator Protein Ligands Produced from a Carbazole Scaffold
Cheng, Hei Wun Alison,Sokias, Renee,Werry, Eryn L.,Ittner, Lars M.,Reekie, Tristan A.,Du, Jonathan,Gao, Quanqing,Hibbs, David E.,Kassiou, Michael
supporting information, p. 8235 - 8248 (2019/10/11)
Development of neuroinflammation agents targeting the translocator protein (TSPO) has been hindered by a common single nucleotide polymorphism (A147T) at which TSPO ligands commonly lose affinity. To this end, carbazole acetamide scaffolds were synthesized and structure activity relationships elaborated to explore the requirements for high-affinity binding to both TSPO wild type (WT) and the polymorphic TSPO A147T. This study reports high binding affinity and nondiscriminating TSPO ligands.
Benzylamines: Synthesis and evaluation of antimycobacterial properties
Meindl,Von Angerer,Schonenberger,Ruckdeschel
, p. 1111 - 1118 (2007/10/02)
The synthesis of benzylamines with various N-alkyl chains and substituents in the aromatic system as well as their evaluation on Mycobacterium tuberculosis H 37 Ra are described. The most active compounds in this test, N-methyl-3-chlorobenzylamine (MIC 10.2 μg/mL), N-methyl-3,5-dichlorobenzylamine (93, MIC 10.2 μg/mL), and N-butyl-3,5-difluorobenzylamine (MIC 6.4 μg/mL), also exhibited a marked inhibitory effect on Mycobacterium marinum and Mycobacterium lufu used for the determination of antileprotic properties. The combination of 93 with aminosalicylic acid, streptomycin, or dapsone exert marked supra-additive effects on M. tuberculosis H 37 Ra.
