143552-72-1

Upstream product

• 2280-44-6 D-Glucose 
• 3282-30-2 pivaloyl chloride 
• 4195-19-1 pivaloyl imidazole 

Downstream Products

• 81058-26-6 1,2,3,4,6-penta-O-trimethylacetyl-β-D-glucopyranose 
• 143552-75-4 1,3,4,6-Tetra-O-pivaloyl-β-D-glucopyranose 
• 143552-74-3 1,2,3,6-tetra-O-pivaloyl-β-D-glucopyranose 

Relevant academic research and scientific papers

Use of N-pivaloyl imidazole as protective reagent for sugars

N-Pivaloyl imidazole was prepared and used as a selective protective reagent of different monosaccharides (D-glucose, D-mannose, D-galactose, 2- acetamido-2-deoxy-D-glucose and 2-acetamido-2-deoxy-β-D-glucopyranosyl azide) and lactose. A variety of pivalates were obtained with moderate or good regioselectivity.

Synthesis and utilization of saccharide intermediates

A new method has been developed for preparation of partially pivaloylated saccharides in one step from readily available starting materials. These intermediates were used in the synthesis of disaccharides and a glucosteroid. A new method has been developed for preparation of partially pivaloylated saccharides in one step from readily available starting materials. These intermediates were used in the synthesis of disaccharides and a glucosteroid.