1435769-89-3Relevant academic research and scientific papers
A carrier-free and recyclable protocol for the cross-coupling of terminal alkynes with arylboronic acids in H2O/TBAB
Tang, Bo-Xiao,Kuang, Ren-Yun,Wen, Ji-Wu,Huang,Zhang, Zhen-Xing,Shen, Yu-Jun,Chen, Jia-Ping,Wu, Wen-Ying
, p. 1975 - 1977 (2019)
A new and recyclable protocol was developed for Pd(OAc)2-catalyzed the cross-coupling reaction of terminal alkynes with arylboronic acids using environmentally friendly H2O/TBAB as reaction medium. A series of cross-coupling products containing internal acetylenic bond can be obtained with good selectivity and yield. The Pd(OAc)2/H2O/TBAB system was stable in the Sonogashira-type cross-coupling reaction and could be used at least three cycles without considerable decrease in catalytic performance. The results suggest that the unsupported and recyclable systems can be extended to the other realm of C&C bond formation in synthetic organic chemistry.
Tri-substituted imidazole analogues of SB203580 as inducers for cardiomyogenesis of human embryonic stem cells
Low, Joo-Leng,Jürjens, Gerrit,Seayad, Jayasree,Seow, Jasmine,Ting, Sherwin,Laco, Filip,Reuveny, Shaul,Oh, Steve,Chai, Christina L.L.
, p. 3300 - 3303 (2013/06/27)
The p38α mitogen-activated protein kinase (MAPK) inhibitor SB203580 had been reported to enhance the cardiomyogenesis of human embryonic stem cells (hESCs). To investigate if tri-substituted imidazole analogues of SB203580 are equally effective inducers f
