1435933-30-4

Basic information

• Product Name: C₂₀H₂₇N₃O₂
• CAS NO: 1435933-30-4
• Molecular Weight: 341.453
• Mol File: 1435933-30-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₂₇N₃O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₂₇N₃O₂(1435933-30-4)
• EPA Substance Registry System: C₂₀H₂₇N₃O₂(1435933-30-4)

Safety Data

• Hazardous Substances Data: 1435933-30-4(Hazardous Substances Data)

Upstream product

• 768378-07-0 tert-butyl 2-(4-tert-butylphenoxy)acetate 
• 98-54-4 para-tert-butylphenol 
• 939376-50-8 N₂-ethyl-N₂-methyl-pyridine-2,5-diamine 
• 1798-04-5 (4-tert-butylphenoxy)acetic acid 
• 154924-16-0 C₈H₁₁N₃O₂ 

Relevant articles and documents

Discovery of potent transient receptor potential vanilloid 1 antagonists: Design and synthesis of phenoxyacetamide derivatives

We aimed to discover a novel type of transient receptor potential vanilloid 1 (TRPV1) antagonist because such antagonists are possible drug candidates for treating various disorders. We modified the structure of hit compound 7 (human TRPV1 IC50 = 411 nM) and converted its pyrrolidino group to a (hydroxyethyl)methylamino group, which substantially improved inhibitory activity (15d; human TRPV1 IC50 = 33 nM). In addition, 15d ameliorated bladder overactivity in rats in vivo.