1436-60-8 Usage
Uses
Used in Pharmaceutical Synthesis:
(1R,2R)-2-AMINO-CYCLOHEXANECARBOXYLIC ACID ETHYL ESTER is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Organic Compounds Synthesis:
In the field of organic chemistry, (1R,2R)-2-AMINO-CYCLOHEXANECARBOXYLIC ACID ETHYL ESTER serves as a crucial building block for the synthesis of a wide range of organic compounds. Its cyclohexane ring and functional groups enable the creation of diverse chemical entities with specific properties and applications.
Used in Chemical Research and Development:
(1R,2R)-2-AMINO-CYCLOHEXANECARBOXYLIC ACID ETHYL ESTER is utilized in chemical research and development to explore its potential applications and properties. Its unique structure and reactivity make it an interesting subject for scientific investigation, leading to advancements in various chemical disciplines.
Check Digit Verification of cas no
The CAS Registry Mumber 1436-60-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,3 and 6 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1436-60:
(6*1)+(5*4)+(4*3)+(3*6)+(2*6)+(1*0)=68
68 % 10 = 8
So 1436-60-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H17NO2/c1-2-12-9(11)7-5-3-4-6-8(7)10/h7-8H,2-6,10H2,1H3/t7-,8+/m1/s1
1436-60-8Relevant academic research and scientific papers
Synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols or 3-amino alcohols using iodobenzene dichloride and sodium azide
He, Tian,Gao, Wen-Chao,Wang, Wei-Kun,Zhang, Chi
, p. 1113 - 1118 (2014/04/03)
A general and efficient method for the synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols and 3-amino alcohols has been developed using the same reagent combination of iodobenzene dichloride (PhICl2) and sodium azide (NaN3).
EXPERIMENTAL STUDIES OF THE ANOMERIC EFFECT. PART 2 RING INVERSION AND NITROGEN INVERSION EQUILIBRIA IN CIS-DECAHYDROQUINAZOLINES
Booth, Harold,Khedhair, Khedhair A.,Al-Shirayda, Hatif A. R. Y.
, p. 1465 - 1476 (2007/10/02)
The positions of conformational equilibria due to the double ring inversion in cis-decahydroquinazoline (7-->//07-->8 1.08 kcal mol-1; -ΔG09-->10 1.10 kcal mol-1) for the conformation which would allow the lone pairs on N(1) and N(3) to lie on the hindered 'inside' face of the molecules.However, the values of 3J(CHNH) coupling constants for both cis-decahydro-3-methylquinazoline (10) and cis (4aH, 8aH) cis (2H, 8aH)-decahydro-2,3-dimethylquinazoline (14) show that the N-inversion equilibrium at N(1) prefers the conformation in which N(1)-H is 'inside' (axial), and N(1)-lone pair equatorial, thus demonstrating the ability of the anomeric effect to outweigh steric repulsions.
