1436-99-3

Basic information

• Product Name: 6-Benzyloxycarbonylamino-2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-hexanoic acid methyl ester
• CAS NO: 1436-99-3
• Molecular Weight: 527.618
• Mol File: 1436-99-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-Benzyloxycarbonylamino-2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-hexanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Benzyloxycarbonylamino-2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-hexanoic acid methyl ester(1436-99-3)
• EPA Substance Registry System: 6-Benzyloxycarbonylamino-2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-hexanoic acid methyl ester(1436-99-3)

Safety Data

• Hazardous Substances Data: 1436-99-3(Hazardous Substances Data)

Upstream product

• 3496-11-5 2,5-dioxopyrrolidin-1-yl (2S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate 
• 27894-50-4 methyl (2S)-2-amino-6-{[(benzyloxy)carbonyl]amino}hexanoate hydrochloride 
• 92619-25-5 N-Me-Cbz-valine 
• 55355-50-5 N^ω-benzyloxycarbonyl-(RS)-lysine methyl ester hydrochloride 
• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 

Downstream Products

• 22677-62-9 L-valyl-L-lysine 
• 32303-80-3 Z-Val-Lys<(N^ε)Z>-NH-NH2 
• 2486-81-9 Z-Val-Lys<(N^ε)Z>-OH 

Relevant articles and documents

Mixed Anhydrides in Peptide Synthesis. Reduction of Urethane Formation and Racemization Using N-Methylpiperidine as the Tertiary Amine Base

The side reactions of urethane formation and racemization accompanying couplings by the mixed anhydride method are reduced when N-methylpiperidine is used as base, the best results being achieved in dichloromethane.