143602-38-4

Basic information

• Product Name: Acetamide, N-[5-(4-nitrophenyl)-4-[5-[(3,4,5,6-tetrahydro-2H-azepin-7-yl)amino]pent yl]-2-thiazolyl]-, monohydrobromide
• CAS NO: 143602-38-4
• Molecular Formula: C22H29N5O3S.BrH
• Molecular Weight: 524.482
• Mol File: 143602-38-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[5-(4-nitrophenyl)-4-[5-[(3,4,5,6-tetrahydro-2H-azepin-7-yl)amino]pent yl]-2-thiazolyl]-, monohydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[5-(4-nitrophenyl)-4-[5-[(3,4,5,6-tetrahydro-2H-azepin-7-yl)amino]pent yl]-2-thiazolyl]-, monohydrobromide(143602-38-4)
• EPA Substance Registry System: Acetamide, N-[5-(4-nitrophenyl)-4-[5-[(3,4,5,6-tetrahydro-2H-azepin-7-yl)amino]pent yl]-2-thiazolyl]-, monohydrobromide(143602-38-4)

Safety Data

• Hazardous Substances Data: 143602-38-4(Hazardous Substances Data)

Upstream product

• 64039-36-7 S-(4-nitrobenzyl)isothiourea hydrobromide 
• 2525-16-8 O-methylcaprolactim 

Relevant articles and documents

Synthesis of 4-(ω-aminoalkyl)- or 4-(ω-lactamiminoalkyl)thiazoles by ring chain transformation of isothioureas with lactam derivatives

CH-Acidic isothioureas 1 react with lactam acetals 2 at the unsubstituted N-atom as well as at the acidic S-methylene group giving 4-(ω-aminoalkyl)thiazoles 6. The latter are further transformed to 4-(ω-lactamiminoalkyl)thiazoles 8, if lactim ethers 3 are used in reactions with isothioureas 1.