143611-09-0Relevant articles and documents
Synthesis and biological activity of 17-chloro-16(17) unsaturated D-homo antiprogestins
Schwede, Wolfgang,Cleve, Arwed,Neef, Guenter,Ottow, Eckhard,Stoeckemann, Klaus,Wiechert, Rudolf
, p. 176 - 180 (1994)
An efficient approach to 17-chloro-16(17) unsaturated D-homo antiprogestins is described.The key steps of the synthesis are a ring-expansion via dichlorocarbene addition to a 17-silyl enol ether and a palladium catalyzed coupling of an 11β-(4-aryltriflate