1436413-21-6

Basic information

• Product Name: 3-benzyl-2-(3′-methylphenyl)quinoline
• CAS NO: 1436413-21-6
• Molecular Weight: 309.411
• Mol File: 1436413-21-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-benzyl-2-(3′-methylphenyl)quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-2-(3′-methylphenyl)quinoline(1436413-21-6)
• EPA Substance Registry System: 3-benzyl-2-(3′-methylphenyl)quinoline(1436413-21-6)

Safety Data

• Hazardous Substances Data: 1436413-21-6(Hazardous Substances Data)

Upstream product

• 591-17-3 meta-bromotoluene 
• 53097-56-6 2-benzyl-3-phenylpropionitrile 
• 100-39-0 benzyl bromide 
• 100-51-6 benzyl alcohol 
• 585-74-0 3-Methylacetophenone 
• 5344-90-1 2-Aminobenzyl alcohol 
• 54095-43-1 1-(3-methylphenyl)-3-phenylpropan-1-one 

Relevant articles and documents

Preparation of 2-arylquinolines from β-arylpropionitriles with aryllithiums and NIS through iminyl radical-mediated cyclization

Treatment of β-arylpropionitriles with aryllithiums, followed by the reaction with water and then with NIS under irradiation with a tungsten lamp gave 2-arylquinolines in good to moderate yields. The present reaction proceeds through the formation of N-iodoimines from imines with NIS, the generation of imino-nitrogen-centered radicals, and their cyclization onto the aromatic rings of the imines to form 2-aryl-3,4-dihydroquinolines. Finally, the oxidation of 2-aryl-3,4-dihydroquinolines with NIS proceeds smoothly to generate 2-arylquinolines.