1436426-81-1

Basic information

• Product Name: tert-butyl 4-(4-(4-chloro-2-(4-(3,3,3-trifluoropropyl)piperazin-1-yl)phenylcarbamoyl)-2,3-difluorobenzyl)-3-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate
• Synonyms: tert-butyl 4-(4-(4-chloro-2-(4-(3,3,3-trifluoropropyl)piperazin-1-yl)phenylcarbamoyl)-2,3-difluorobenzyl)-3-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate
• CAS NO: 1436426-81-1
• Molecular Weight: 718.164
• Mol File: 1436426-81-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-(4-(4-chloro-2-(4-(3,3,3-trifluoropropyl)piperazin-1-yl)phenylcarbamoyl)-2,3-difluorobenzyl)-3-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(4-(4-chloro-2-(4-(3,3,3-trifluoropropyl)piperazin-1-yl)phenylcarbamoyl)-2,3-difluorobenzyl)-3-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate(1436426-81-1)
• EPA Substance Registry System: tert-butyl 4-(4-(4-chloro-2-(4-(3,3,3-trifluoropropyl)piperazin-1-yl)phenylcarbamoyl)-2,3-difluorobenzyl)-3-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate(1436426-81-1)

Safety Data

• Hazardous Substances Data: 1436426-81-1(Hazardous Substances Data)

Upstream product

• 1436426-79-7 1-(5-chloro-2-nitrophenyl)-4-(3,3,3-trifluoropropyl)piperazine 
• 462073-61-6 1-(5-chloro-2-nitrophenyl)piperazine 
• 700-37-8 4-chloro-2-fluoro-nitrobenzene 
• 261763-37-5 2,3-difluoro-4-methylbenzoic acid 
• 1174632-70-2 4-(bromomethyl)-2,3-difluorobenzoic acid 
• 1436426-21-9 4-chloro-2-(4-(3,3,3-trifluoropropyl)piperazin-1-yl)aniline 
• 183742-33-8 3-(methoxycarbonylmethyl)piperazine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 1436421-89-4 2-(1-(4-(4-chloro-2-(4-(3,3,3-trifluoropropyl)piperazin-1-yl)phenylcarbamoyl)-2,3-difluorobenzyl)piperazin-2-yl)acetic acid 

Relevant articles and documents

MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO

The present invention relates to compounds of Formula (I) and pharmaceutically acceptable salts, solvates, and hydrates thereof that are useful in methods of treatment and alleviation of diseases and disorders of the heart, brain, kidney, immune, and reproductive system resulting from ischemia, or reperfusion subsequent to ischemia, and any downstream complication(s) related thereto. The present invention further relates to methods of treatment and alleviation of diseases and disorders of the vasculature resulting from vasoconstriction or hypertension and any downstream complication(s) resulting from elevated blood pressure and/or reduced tissue perfusion.