1436463-08-9Relevant articles and documents
Catalytic asymmetric one-pot synthesis of α-methylene-γ-lactams
Companyó, Xavier,Geant, Pierre-Yves,Mazzanti, Andrea,Moyano, Albert,Rios, Ramon
, p. 75 - 82 (2014/01/06)
An organocatalytic enantioselective synthesis of α-methylene-γ- lactams has been developed. The reaction between protected 2-aminomalonates and Morita-Baylis-Hillman carbonates is catalyzed by chiral Lewis bases to afford the corresponding lactams in exce