14365-73-2 Usage
Description
1-Amino-1-deoxy-2,3,4-triacetate β-D-Glucopyranuronic Acid Methyl Ester is a complex organic compound derived from the modification of β-D-Glucopyranuronic Acid. It features an amino group at the first position, devoid of a hydroxyl group, and is esterified with a methyl group. Additionally, it has three acetate groups at the second, third, and fourth positions, which contribute to its unique chemical properties and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
1-Amino-1-deoxy-2,3,4-triacetate β-D-Glucopyranuronic Acid Methyl Ester is used as a pharmaceutical intermediate for the development of drugs targeting specific biological interactions. Its unique structure allows it to be a potential candidate in the design and synthesis of novel therapeutic agents.
Used in Biological Studies:
1-Amino-1-deoxy-2,3,4-triacetate β-D-Glucopyranuronic Acid Methyl Ester is used as a research tool in biological studies for the inhibitor identification of fibroblast growth factor (FGF-2) binding to heparin and endothelial cells. Its specific structural features enable it to interfere with the binding process, providing valuable insights into the molecular mechanisms underlying FGF-2 signaling and its role in various biological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 14365-73-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,3,6 and 5 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 14365-73:
(7*1)+(6*4)+(5*3)+(4*6)+(3*5)+(2*7)+(1*3)=102
102 % 10 = 2
So 14365-73-2 is a valid CAS Registry Number.
14365-73-2Relevant articles and documents
-
Lee,Lee
, p. 302,305,306 (1978)
-
Synthesis of N-(β-d-glycuronopyranosyl)alkanamides and 1-(β-d-glycuronopyranosyl)-4-phenyl-[1,2,3]-triazoles as N-glycoprotein linkage region analogs: Examination of the effect of C5 substituent on the N-glycosidic torsion (ΦN) based on X-ray c
Mathiselvam, Manoharan,Loganathan, Duraikkannu,Varghese, Babu
, p. 1 - 8 (2013/10/01)
The torsion angle around the N-glycoprotein linkage region (GlcNAc-Asn) is an important factor for presenting sugar on the cell surface which is crucial for many biological processes. Earlier studies using model and analogs showed that this important tors
Synthesis of a glucuronic acid and glucose conjugate library and evaluation of effects on endothelial cell growth
Pitt, Nigel,Duane, Rhona M.,O' Brien, Alan,Bradley, Helena,Wilson, Stephen J.,O' Boyle, Kathy M.,Murphy, Paul V.
, p. 1873 - 1887 (2007/10/03)
Compounds that alter endothelial cell growth are of interest in the development of angiogenesis modulators. A structurally diverse series of saccharide derivatives (glycosylamide conjugates) have been synthesized and evaluated for their effects on bovine
