3082-96-0

Basic information

• Product Name: 1,2,3,4-TETRA-O-ACETYL-D-GLUCOPYRANURONIC ACID METHYL ESTER
• Synonyms: 1,2,3,4-TETRA-O-ACETYL-D-GLUCOPYRANURONIC ACID METHYL ESTER;1,2,3,4-TETRA-O-ACETYL-D-GLUCURONIC ACID METHYL ESTER;METHYL 1,2,3,4-TETRA-O-ACETYL-D-GLUCOPYRANOSIDURONATE;METHYL 1,2,3,4-TETRA-O-ACETYL-D-GLUCOPYRANURONATE;METHYL-1,2,3,4-TETRA-O-ACETYL-D-GLUCORONATE;METHYL 1,2,3,4-TETRA-O-ACETYL-D-GLUCURONATE;D-Glucopyranuronic acid, methyl ester, tetraacetate;1,2,3,4-Tetra-O-acetyl-D-glucuronidemethylester
• CAS NO: 3082-96-0
• Molecular Formula: C₁₅H₂₀O₁₁
• Molecular Weight: 376.31
• Product Categories: Carbohydrates & Derivatives
• Mol File: 3082-96-0.mol

Chemical Properties

• Melting Point: 103-105°C
• Boiling Point: 412.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.33±0.1 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Very Slightly)
• CAS DataBase Reference: 1,2,3,4-TETRA-O-ACETYL-D-GLUCOPYRANURONIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4-TETRA-O-ACETYL-D-GLUCOPYRANURONIC ACID METHYL ESTER(3082-96-0)
• EPA Substance Registry System: 1,2,3,4-TETRA-O-ACETYL-D-GLUCOPYRANURONIC ACID METHYL ESTER(3082-96-0)

Safety Data

• Hazardous Substances Data: 3082-96-0(Hazardous Substances Data)

Usage

Uses

1. Used in Organic Synthesis:
1,2,3,4-TETRA-O-ACETYL-D-GLUCOPYRANURONIC ACID METHYL ESTER is used as an intermediate in organic synthesis for the production of various complex organic compounds. Its unique structure allows for further functionalization and modification, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
2. Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,2,3,4-TETRA-O-ACETYL-D-GLUCOPYRANURONIC ACID METHYL ESTER is used as a key component in the development of novel drug candidates. Its versatile chemical structure enables the creation of new molecules with potential therapeutic applications, such as anti-inflammatory, anti-cancer, or anti-infective agents.
3. Used in Research and Development:
1,2,3,4-TETRA-O-ACETYL-D-GLUCOPYRANURONIC ACID METHYL ESTER is also utilized in research and development laboratories for the study of carbohydrate chemistry, glycobiology, and the development of new methodologies for the synthesis of complex carbohydrates and their derivatives. Its unique structure and reactivity make it an essential tool for understanding the role of carbohydrates in biological systems and the development of new therapeutic strategies.
4. Used in Material Science:
In the field of material science, 1,2,3,4-TETRA-O-ACETYL-D-GLUCOPYRANURONIC ACID METHYL ESTER can be employed as a component in the development of advanced materials with specific properties, such as stimuli-responsive hydrogels, drug delivery systems, or biocompatible coatings for medical devices. Its ability to form hydrogen bonds and interact with other molecules makes it a promising candidate for the design of novel materials with tailored properties.

Upstream product

• 487-44-5 D-(+)-glucuronic acid γ-lactone 
• 108-24-7 acetic anhydride 
• 63-29-6 D-glucurono-6,3-lactone 
• 67-56-1 methanol 
• 6556-12-3 D-glucuronic acid 
• 1190935-89-7 D-glucurono-6,3-lactone 
• 82228-14-6 methyl D-glucopyranuronate 

Downstream Products

• 21085-72-3 1-bromo-2,3,4-tri-O-acetyl-α-D-glucuronic acid methyl ester 
• 67776-38-9 2,3,4-tri-O-acetyl-1-azido-1-deoxy-β-D-glucopyranuronic acid methyl ester 
• 14365-73-2 2,3,4-tri-O-acetyl-β-D-glucopyranosylamine uronic acid methyl ester 
• 1350467-71-8 methyl (phenyl 2,3-di-O-acetyl-4-deoxy-1-thio-α-L-threo-hex-4-enopyranosid)uronate 
• 52173-67-8 methyl (2,4,6-trichlorophenyl 2,3,4-tri-O-acetyl-β-D-glucopyranosid)uronate 
• 1350467-75-2 methyl (2,4,6-trichlorophenyl 2,3-di-O-acetyl-4-deoxy-α-L-threo-hex-4-enopyranosid)uronate 
• 1350467-76-3 C₁₇H₁₅⁽²⁾H₂Cl₃O₈ 
• 1350467-77-4 methyl (2,4,6-trichlorophenyl 2,3-di-O-acetyl-4-deoxy-5-C-bromo-4-{²H}-β-D-glucopyranosid)uronate 
• 1350467-78-5 methyl (2,4,6-trichlorophenyl 2,3-di-O-acetyl-4-deoxy-4-{(2)H}-α-L-threo-hex-4-enopyranosid)uronate 
• 1350467-79-6 methyl (phenyl 4-deoxy-5-C-methoxy-β-D-glucopyranosid)uronate 
• 1350467-81-0 phenyl 4-deoxy-5-C-methoxy-β-D-glucopyranosiduronic acid 
• 1350467-68-3 phenyl 4-deoxy-1-thio-α-L-threo-hex-4-enopyranosiduronic acid 
• 1350467-69-4 2,4,6-trichlorophenyl 4-deoxy-α-L-threo-hex-4-enopyranosiduronic acid 
• 1350467-70-7 2,4,6-trichlorophenyl 4-deoxy-4-{(2)H}-α-L-threo-hex-4-enopyranosiduronic acid 

Relevant articles and documents

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CONJUGATES COMPRISING SELF-IMMOLATIVE GROUPS AND METHODS RELATED THERETO

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In some aspects, the invention relates to an antibody-drug conjugate, comprising an anti-CD 19 antibody; a linker; and an active agent. The antibody-drug conjugate may comprise a self-immolative group. The linker may comprise an O-substituted oxime, e.g., wherein the oxygen atom of the oxime is substituted with a group that covalently links the oxime to the active agent; and the carbon atom of the oxime is substituted with a group that covalently links the oxime to the antibody.

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COMPOUNDS COMPRISING SELF-IMMOLATIVE GROUP

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