143658-46-2

Upstream product

• 143658-45-1 2-(2,6,6-trimethyl-2-cyclohexenyl)ethanal 
• 1104-78-5 dimethyl 2-(triphenylphosphoranylidene)succinate 
• 143658-43-9 ethyl <2,6,6-trimethyl-2-cyclohexenyl>acetate 
• 143658-44-0 2-<(S)-2,6,6-trimethyl-2-cyclohexenyl>ethanol 
• 134780-16-8 (R)-2,4,4-trimethyl-2-cyclohexen-1-ol 

Downstream Products

• 143728-94-3 3-formyl-5-(2,6,6-trimethyl-2-cyclohexenyl)-3-pentenal 
• 143658-47-3 3-hydroxymethyl-5-(2,6,6-trimethyl-2-cyclohexenyl)-3-penten-1-ol 

Relevant academic research and scientific papers

Synthesis of Mono- and Sesqui-terpenoids. XXI. Synthesis and Absolute Configuration of (E)-3-Formyl-(2,6,6-trimethyl-2-cyclohexenyl)-3-pentenal, a Sesquiterpenoid from a Marine Alga, Caulerpa ashmeadii

A six-step synthesis of the enantiomers of (E)-3-formyl-(2,6,6-trimethyl-2-cyclohexenyl)-3-pentenal has been achieved, starting from the enantiomers of 2,4,4-trimethyl-2-cyclohexenol.By comparing the sign of the optical rotation of the naturally occurring

APPLICATION OF BIOCHEMICAL METHODS IN ENANTIOSELECTIVE SYNTHESIS OF BIOACTIVE NATURAL PRODUCTS

Enzymes as well as yeasts were used in enantioselective syntheses of bioregulators such as hormones and semiochemicals.Lipases and esterases were employed in achieving optical resolution, conversion of meso-compounds to optically active compounds, and macrolactonization.Lactase effected glucosidation of a phenolic hydroxy ketone without any protection of the functional groups.Yeasts provided a variety of optically active hydroxy esters and ketones, which served as versatile non-racemic chiral building blocks.