1436581-85-9Relevant academic research and scientific papers
Ring-Opening/Recyclization Cascades of Monoactivated Cyclopropanes
Mishra, Uttam K.,Patel, Kaushalendra,Ramasastry, S. S. V.
supporting information, (2020/05/25)
A variety of cyclopropyl aryl ketones undergo uncatalyzed cascade ring-opening/recyclization reactions to generate indenones and fluorenones. In addition, a new strategy to access 3-hydroxyindanones possessing two contiguous stereogenic centers, one of th
Beyond the Corey–Chaykovsky Reaction: Synthesis of Unusual Cyclopropanoids via Desymmetrization and Thereof
Patel, Kaushalendra,Mishra, Uttam K.,Mukhopadhyay, Dipto,Ramasastry
supporting information, p. 4568 - 4571 (2019/11/03)
Desymmetrization-based protocols for the synthesis of highly functionalized indeno-spirocyclopropanes and cyclopropa-fused indanes have been established through unexpected reactions triggered by the Corey–Chaykovsky reagent. These structures were further elaborated in one step to privileged scaffolds such as fluorenones, indenones, and naphthaphenones. For instance, an acid-catalyzed transformation of indeno-spirocyclopropanes provided fluorenones via a homo-Nazarov-type cyclization, and naphthaphenones were obtained via an acid-catalyzed cyclopropane ring-opening/retro-Michael sequence.
Synthesis of Cyclopropanoids via Substrate-Based Cyclization Pathways
Mishra, Uttam K.,Patel, Kaushalendra,Ramasastry
supporting information, p. 175 - 179 (2019/01/04)
A series of unexpected reactions triggered by the dimethyloxosulfonium methylide led to the discovery of unconventional approaches for the synthesis of cyclopropa-fused tetralones and indeno-spirocyclopropanes. These highly functionalized structures were further elaborated in one step to privileged scaffolds such as tetralones, indenones, and fluorenones. As a whole, the results presented herein establish new diversity-oriented folding pathways.
Synthesis of 2,3-diarylfluorenones by domino 'twofold Heck/ electrocyclization/dehydrogenation' reactions of 2,3-dibromoindenone
Akrawi, Omer A.,Khan, Afsar,Hussain, Munawar,Mohammed, Hamid H.,Villinger, Alexander,Langer, Peter
, p. 3037 - 3039 (2013/06/27)
Abstract Domino double Heck/electrocyclization/dehydrogenation reactions of 2,3-dibromo-1H-inden-1-one with styrenes provide a convenient synthesis of 2,3-diarylfluorenones.
