14367-72-7Relevant academic research and scientific papers
Double parallel dynamic resolution through lipase-catalyzed asymmetric transformation
Zhang, Yan,Hu, Lei,Ramstr?m, Olof
supporting information, p. 1805 - 1807 (2013/03/14)
Dynamic systems based on double parallel reactions have been generated and resolved in situ by secondary lipase-catalyzed asymmetric transformation, resulting in high chemo- and enantioselectivities.
Direct asymmetric dynamic kinetic resolution by combined lipase catalysis and nitroaldol (Henry) reaction
Vongvilai, Pornrapee,Larsson, Rikard,Ramstroem, Olof
supporting information; experimental part, p. 448 - 452 (2009/04/10)
The asymmetric synthesis of β-nitroalkanol derivatives was simply achieved by a combined nitroaldol (Henry) reaction with lipase-catalyzed transesterification in high yield and enantiomeric purity (up to 92% and 99% ee) through a direct one-pot procedure.
Dynamic combinatorial resolution: Direct asymmetric lipase-mediated screening of a dynamic nitroaldol library
Vongvilai, Pornrapee,Angelin, Marcus,Larsson, Rikard,Ramstroem, Olof
, p. 948 - 950 (2008/02/01)
(Chemical Equation Presented) A disturbance in the library: The nitroaldol (Henry) reaction was developed as an efficient C-C bond-forming route to dynamic combinatorial libraries (DCLs). These DCLs generated under thermodynamic control were coupled in a
