14367-96-5

Basic information

• Product Name: 1-(3-bromophenyl)-2-nitroethanone
• Synonyms: 1-(3-bromophenyl)-2-nitroethanone
• CAS NO: 14367-96-5
• Molecular Weight: 244.045
• Mol File: 14367-96-5.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 1-(3-bromophenyl)-2-nitroethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-bromophenyl)-2-nitroethanone(14367-96-5)
• EPA Substance Registry System: 1-(3-bromophenyl)-2-nitroethanone(14367-96-5)

Safety Data

• Hazardous Substances Data: 14367-96-5(Hazardous Substances Data)

Upstream product

• 3132-99-8 m-bromobenzoic aldehyde 
• 585-76-2 m-bromobenzoic acid 
• 25854-38-0 sodium nitromethane 
• 39220-96-7 1-(3-bromophenyl)-2-nitroethanol 
• 75-52-5 nitromethane 
• 314767-38-9 (1H-benzo[d][1,2,3]triazol-1-yl)(3-bromophenyl)methanone 
• 91240-83-4 1-(3-bromo-benzoyl)-1H-imidazole 

Downstream Products

• 14547-41-2 1-(3-bromo-phenyl)-3-morpholin-4-yl-2-nitro-propan-1-one 
• 1194628-13-1 5-(3-bromophenyl)-2-phenyloxazole 
• 1100273-65-1 (S)-(+)-1-(3-bromophenyl)-2-nitroethanol 
• 630050-32-7 3-bromo-N-(4-methylbenzenesulfonyl)benzenecarboxamide 
• 618-89-3 methyl 3-bromobenzoate 
• 74048-09-2 2-methyl-5-(m-bromophenyl)oxazole 
• 1044833-29-5 (R)-(-)-1-(3-bromophenyl)-2-nitroethanol 
• 745079-14-5 ethyl 5-(3-bromophenyl)-4-nitroisoxazole-3-carboxylate 

Relevant articles and documents

Facile synthesis of 2-nitromethyl aromatic ketones by insertion of benzynes into the C-C bond of α-nitroketones

A facile method to synthesize 2-nitromethyl aromatic ketones was developed. In the method, benzyne was generated in situ for the insertion to α-Nitroketones in one pot to achieve 2-nitromethyl aromatic ketones under mild conditions. Aromatic and aliphatic α-nitroketones were applied in the reaction, and the results show that aliphatic α-nitroketones gave excellent yields (up to 96%), while aromatic α-nitroketones gave moderate yields. The synthesized 2-nitromethyl aromatic ketones could be potential substrates to synthesize isoindoles.

Organocatalytic Asymmetric Domino Michael/Acyl Transfer Reaction Between α-Nitroketones and in situ-Generated ortho-Quinone Methides: Route to 2-(1-Arylethyl)phenols

An organocatalytic asymmetric domino Michael/acyl transfer reaction between α-nitroketones and o-quinone methides is disclosed. o-Quinone methides are generated in situ from 2-sulfonylmethylphenols in basic medium. With 10 mol% of bifunctional squaramide catalyst, high yields and excellent enantioselectivities are achieved for a variety of O-acyl 2-(1-arylethyl)phenols under mild reaction condition. (Figure presented.).

Unexpected C-C bond cleavage of α-nitroketone in the presence of TsNBr2: A new pathway for C-N bond formation

A new catalyst-free protocol for C-N bond formation via the cleavage of α-nitroketone has been developed. When α-nitroketones are treated with TsNBr2 in the presence of potassium carbonate, unexpected cleavage of C(O)-CHNO2 bond of α-nitroketone was observed followed by the formation of corresponding amide. Various nitroketones could be converted to corresponding amide using this procedure.