74048-09-2Relevant academic research and scientific papers
Iron-promoted practical one-pot synthesis of 2,5-disubstituted oxazoles
Chen, Songhui,Bai, Donghu,Shi, Feng,Li, Jian,Li, Chunju,Jia, Xueshun
experimental part, p. 1464 - 1468 (2012/09/07)
A practical one-pot protocol for the synthesis of 2,5-disubstituted oxazoles from 1-aryl-2-nitroethanones was reported. In the presence of iron/AcOH in acetonitrile, the reaction of 1-aryl-2-nitroethanones with trimethyl orthoacetate or trimethyl orthobenzoate delivered the corresponding 2,5-disubstituted oxazoles in moderate to good yields. Copyright
