143680-11-9

Upstream product

• 74924-27-9 methyl (S)-3-benzyloxy-2-methylpropanoate 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 63930-49-4 (R)-3-(benzyloxy)-2-methylpropan-1-ol 
• 72657-23-9 methyl (R)-3-hydroxy-2-methylpropionate 
• 21382-82-1 (carbethoxyethylidene)triphenylphosphorane 
• 79027-28-4 (2S)-3-(benzyloxy)-2-methylpropanal 

Downstream Products

• 373645-82-0 (E)-(R)-5-Benzyloxy-2,4-dimethyl-pent-2-enal 
• 905732-34-5 (E)-(2S,4R,5R,8R)-9-Benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-4,6,8-trimethyl-non-6-en-3-one 
• 905732-37-8 (E)-(2R,3R,6R)-7-Benzyloxy-2-[(4S,5S)-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxolan-4-yl]-4,6-dimethyl-hept-4-en-3-ol 
• 905732-38-9 (2S,3S,4R,5R,6R)-1-Benzyloxy-6-[(4S,5S)-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxolan-4-yl]-2,4-dimethyl-heptane-3,4,5-triol 
• 1027036-65-2 (E)-(2S,4R,5R,8R)-9-Benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-4,6,8-trimethyl-5-triisopropylsilanyloxy-non-6-en-3-one 
• 905732-35-6 (E)-(2S,4R,5R,8R)-9-Benzyloxy-4,6,8-trimethyl-2-triethylsilanyloxy-5-triisopropylsilanyloxy-non-6-en-3-one 
• 905732-46-9 (3R,4S,5S)-4-(tert-Butyl-dimethyl-silanyloxy)-5-{(1R,2S)-1-(tert-butyl-dimethyl-silanyloxy)-2-[(4S,5S)-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxolan-4-yl]-propyl}-3,5-dimethyl-dihydro-furan-2-one 
• 905732-36-7 (E)-(2S,3S,4S,5R,8R)-9-Benzyloxy-4,6,8-trimethyl-2-triethylsilanyloxy-5-triisopropylsilanyloxy-non-6-en-3-ol 
• 905732-39-0 (2S,3S,4R,5R,6S)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-[(4S,5S)-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxolan-4-yl]-2,4-dimethyl-heptane-1,4-diol 
• 905732-40-3 (2S,3S,4R,5R,6S,7S,8S)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-7-(4-methoxy-benzyloxy)-2,4,6-trimethyl-nonane-1,4,8-triol 
• 905732-42-5 Acetic acid (2S,3S,4R,5R,6S,7S,8S)-8-acetoxy-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-7-(4-methoxy-benzyloxy)-2,4,6-trimethyl-nonyl ester 
• 905732-43-6 (2S,3S,4R,5R,6S,7S,8S)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-7-(4-methoxy-benzyloxy)-2,4,6-trimethyl-4-triethylsilanyloxy-nonane-1,8-diol 
• 905732-44-7 (2R,3S,4S,5R,6S,7S)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-7-(4-methoxy-benzyloxy)-2,4,6-trimethyl-8-oxo-4-triethylsilanyloxy-nonanoic acid 
• 905732-45-8 (2R,3S,4S,5R,6S,7S,8S)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-8-hydroxy-7-(4-methoxy-benzyloxy)-2,4,6-trimethyl-4-triethylsilanyloxy-nonanoic acid 

Relevant academic research and scientific papers

1,5-stereocontrol in bismuth-mediated reactions between aldehydes and allyl bromides: Stereoselective synthesis of open-chain all-syn- and anti, anti-1,3,5-disposed trimethylalkanes

The reaction of 5-benzyloxy-2,4-dimethylpent-2-enyl bromide with the bismuth species generated by reduction of bismuth(III) iodide by zinc powder gives an intermediate which reacts with aldehydes with useful levels of stereocontrol in favour of 1,5-anti-(3E)-5-methylalk-3-enols. Manipulation of protecting groups, stereoselective hydrogenation, and tosylate displacement using a higher-order cyanomethylcuprate leads to either all-syn or anti, anti-1,3,5-disposed trimethylalkanes. Georg Thieme Verlag Stuttgart.

Studies directed towards the synthesis of botcinolides: synthesis of the nonalactone ring of 2-epibotcinolide

Synthesis of the polyoxygenated nonalactone ring of 2-epibotcinolide was achieved using a highly stereoselective aldol reaction of the titanium enolate from a lactate-derived chiral ketone, a stereoselective dihydroxylation and a Yamaguchi macrolactonizat