143706-52-9

Upstream product

• 143706-51-8 Dibromopentanyl O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-O-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-3,4,6-tri-O-benzyl-α-D-mannopyranoside 
• 253683-39-5 8-(4,4'-dimethoxytrityloxy)oct-4(Z)-en-1-ol 
• 108869-64-3 2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl trichloroacetimidate 

Downstream Products

• 143706-53-0 Dibromopentanyl O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-O-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-O-<(3,4,6-tri-O-benzyl-α-D-mannopyranosyl-(1->3)>-6-O-(chloroacetyl)-2,4-di-O-benzyl-α-D-mannopyranoside 

Relevant academic research and scientific papers

n-Pentenyl mannoside precursors for synthesis of the nonamannan component of high mannose glycoproteins

The high-mannose oligosaccharide 1 is present on the conserved V3 loop of the viral coat of HIV1 known as GP-120. The mannan portion of this molecule has been prepared by utilization of halogen-promoted n-pentenyl glycoside (NPG) coupling. Two advantageou

Solid-phase oligosaccharide synthesis: preparation of complex structures using a novel linker and different glycosylating agents.

[formula: see text] A beta-(1-->4)-linked trisaccharide was prepared in 53% yield on a polymer support using glycosyl phosphates and released by cross-metathesis of a novel linker to reveal the anomeric n-pentenyl glycoside. Heptasaccharide 33 was prepared in 9% yield in 14 steps.