n-Pentenyl mannoside precursors for synthesis of the nonamannan component of high mannose glycoproteins

DOI: 10.1021/jo00095a020

Source and publish data:

Journal of Organic Chemistry p. 4443 - 4449 (1994)

Update date:2022-08-05

Topics: Synthesis Precursors Glycoproteins Experimental

Authors:

Merritt Merritt

Naisang Naisang

Fraser-Reid

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Article abstract of DOI:10.1021/jo00095a020

The high-mannose oligosaccharide 1 is present on the conserved V3 loop of the viral coat of HIV1 known as GP-120. The mannan portion of this molecule has been prepared by utilization of halogen-promoted n-pentenyl glycoside (NPG) coupling. Two advantageou

Full text of DOI:10.1021/jo00095a020

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Product name:Pentenyl O-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-O-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-3,4,6-tri-O-benzyl-α-D-mannopyranoside

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