1437598-70-3Relevant academic research and scientific papers
Stereoselective total synthesis of 4-ketoclonostachydiol
Rajaram, Singanaboina,Ramulu, Udugu,Ramesh, Dasari,Prabhakar, Peddikotla,Venkateswarlu, Yenamandra
, p. 2115 - 2123 (2013)
An efficient stereoselective total synthesis of the bioactive 14-membered natural macrocyclic bislactone 4-ketoclonostachydiol is described. The strategy involves a Jacobsen's hydrolytic kinetic resolution (HKR), epoxide opening, MacMillan α-hydroxylation, Horner-Wadsworth-Emmons olefination, a Grignard reaction, and Hoveyda-Grubbs-II-catalyzed ring-closing metathesis (RCM) as key steps.
Total synthesis of a 6,6-spiroketal metabolite, dinemasone A
Raji Reddy, Chada,Srikanth, Boinapally,Dilipkumar, Uredi,Rao, Kakita Veera Mohana,Jagadeesh, Bharatam
, p. 525 - 532 (2013/02/26)
The stereoselective total synthesis of dinemasone A has been accomplished. The key reactions, Sharpless asymmetric epoxidation, lithium-mediated epoxy alcohol opening, and double-intramolecular hetero-Michael addition, gave access to dinemasone A from lac
