143765-02-0 Usage
Description
S-(2-Acetamidoethyl) cyclohexanecarbothioate is a chemical compound with the molecular formula C11H19NO2S. It is a thioester derivative of acetaminophen, a commonly used over-the-counter pain reliever and fever reducer. S-(2-Acetamidoethyl) cyclohexanecarbothioate is characterized by its unique structural features and functional groups, making it a valuable tool in medicinal chemistry research for the design and development of new drugs and therapeutics.
Uses
Used in Pharmaceutical Synthesis:
S-(2-Acetamidoethyl) cyclohexanecarbothioate is used as an intermediate in the synthesis of pharmaceuticals. Its unique structure allows it to be a key component in the creation of new medications, potentially leading to advancements in the treatment of various health conditions.
Used in Agrochemical Production:
In addition to its pharmaceutical applications, S-(2-Acetamidoethyl) cyclohexanecarbothioate is also utilized as an intermediate in the production of agrochemicals. This makes it a valuable asset in the development of new agricultural products, such as pesticides and herbicides, to improve crop yields and protect plants from pests.
Used in Organic Synthesis:
S-(2-Acetamidoethyl) cyclohexanecarbothioate serves as a building block in organic synthesis, enabling the creation of new compounds with potential therapeutic or agricultural applications. Its versatility in chemical reactions allows researchers to explore a wide range of possibilities for developing innovative products.
Used in Medicinal Chemistry Research:
Due to its structural features and functional groups, S-(2-Acetamidoethyl) cyclohexanecarbothioate is a valuable tool in medicinal chemistry research. It aids researchers in the design and development of new drugs and therapeutics, contributing to the advancement of medical science and the improvement of human health.
Check Digit Verification of cas no
The CAS Registry Mumber 143765-02-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,7,6 and 5 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 143765-02:
(8*1)+(7*4)+(6*3)+(5*7)+(4*6)+(3*5)+(2*0)+(1*2)=130
130 % 10 = 0
So 143765-02-0 is a valid CAS Registry Number.
143765-02-0Relevant articles and documents
A mechanism-based fluorescence transfer assay for examining ketosynthase selectivity
Prasad, Gitanjeli,Borketey, Lawrence S.,Lin, Tsung-Yi,Schnarr, Nathan A.
supporting information; experimental part, p. 6717 - 6723 (2012/09/22)
Since their discovery, polyketide synthases have received massive attention from researchers hoping to harness their potential as a platform for generating new and improved therapeutics. Despite significant strides toward this end, inherent specificities within the enzymes responsible for polyketide production have severely limited these efforts. We have developed a mechanism-based, fluorescence transfer assay for a key enzyme component of all polyketide synthases, the ketosynthase domain. As demonstrated, this method can be used with both ketosynthase-containing didomains and full modules. As proof of principle, the ketosynthase domain from module 6 of the 6-deoxyerythronolide synthase is examined for its ability to accept a variety of simple thioester substrates. Consistent with its natural hexaketide substrate, we find that this ketosynthase prefers longer, α-branched thioesters and its ability to distinguish these structural features is quite remarkable. Substrate electronics are also tested via a variety of p-substituted aromatic groups. In all, we expect this technique to find considerable use in the field of polyketide biosynthesis and engineering due to its extraordinary simplicity and very distinct visible readout.
