1437798-90-7

Basic information

• Product Name: 4-ethyl 3-methyl 5-acetyl-1-(4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,4-dicarboxylate
• Synonyms: 4-ethyl 3-methyl 5-acetyl-1-(4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,4-dicarboxylate
• CAS NO: 1437798-90-7
• Molecular Weight: 387.433
• Mol File: 1437798-90-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-ethyl 3-methyl 5-acetyl-1-(4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,4-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ethyl 3-methyl 5-acetyl-1-(4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,4-dicarboxylate(1437798-90-7)
• EPA Substance Registry System: 4-ethyl 3-methyl 5-acetyl-1-(4-methoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,4-dicarboxylate(1437798-90-7)

Safety Data

• Hazardous Substances Data: 1437798-90-7(Hazardous Substances Data)

Upstream product

• 50845-77-7 N-(4-methoxy)phenylglycine ethyl ester 
• 105-45-3 acetoacetic acid methyl ester 
• 123-54-6 acetylacetone 
• 104-94-9 4-methoxy-aniline 
• 924-44-7 glyoxylic acid ethyl ester 
• 20010-38-2 4-(4-methoxyphenyl)imino-3-pentene-2-one 

Relevant articles and documents

Copper-Catalyzed Aerobic Cascade Oxidative Coupling/Cyclization for the Construction of 1,4-Dihydropyridine Derivatives

An efficient copper-catalyzed cascade cyclization reaction for the preparation of polysubstituted 1,4-dihydropyridines between N-arylglycine esters and 1,3-dicarbonyl compounds using molecular oxygen as the terminal oxidant has been described. Various N-arylglycine esters 1 and 1,3-dicarbonyl compounds 2 were able to undergo the cascade reaction smoothly to afford the desired products 3 in satisfactory yields. The cascade reaction has the advantages of good functional group tolerance and mild reaction conditions. A possible mechanism has also been proposed on the basis of control experiments.