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1438000-08-8

N-(3-fluorobenzyl)benzisothiazol-3-one-2-amide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1438000-08-8 Structure

  • Basic information

    1. Product Name: N-(3-fluorobenzyl)benzisothiazol-3-one-2-amide
    2. Synonyms: N-(3-fluorobenzyl)benzisothiazol-3-one-2-amide
    3. CAS NO:1438000-08-8
    4. Molecular Formula:
    5. Molecular Weight: 302.329
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1438000-08-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-(3-fluorobenzyl)benzisothiazol-3-one-2-amide(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-(3-fluorobenzyl)benzisothiazol-3-one-2-amide(1438000-08-8)
    11. EPA Substance Registry System: N-(3-fluorobenzyl)benzisothiazol-3-one-2-amide(1438000-08-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1438000-08-8(Hazardous Substances Data)

1438000-08-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1438000-08-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,3,8,0,0 and 0 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1438000-08:
(9*1)+(8*4)+(7*3)+(6*8)+(5*0)+(4*0)+(3*0)+(2*0)+(1*8)=118
118 % 10 = 8
So 1438000-08-8 is a valid CAS Registry Number.

1438000-08-8Downstream Products

1438000-08-8Relevant articles and documents

Design, synthesis and evaluation of 1,2-benzisothiazol-3-one derivatives as potent caspase-3 inhibitors

Liu, Dazhi,Tian, Zhen,Yan, Zhihui,Wu, Lixin,Ma, Yan,Wang, Quan,Liu, Wei,Zhou, Honggang,Yang, Cheng

, p. 2960 - 2967 (2013/07/28)

A number of 1,2-benzisothiazol-3-one derivatives were prepared through structural modification of the original compound from high-throughput screening. Some analogues (e.g., 6b, 6r, 6s and 6w) were identified as novel and potent caspase inhibitors with IC50 of nanomolar. Structure-activity relationship (SAR) studies for caspase-3 inhibition were evaluated in vitro. Molecular modeling studies provided further insight into the interaction of this class of compounds with activated caspase-3. The present small molecule caspase-3 inhibitor with novel structures different from structures of known caspase inhibitors revealed a new direction for therapeutic strategies directed against diseases involving abnormally up-regulated apoptosis.

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