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143815-07-0

Benzene, 5-(1-cyclopenten-1-yl)-1,2,3-trimethoxy- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 143815-07-0 Structure

  • Basic information

    1. Product Name: Benzene, 5-(1-cyclopenten-1-yl)-1,2,3-trimethoxy-
    2. Synonyms:
    3. CAS NO:143815-07-0
    4. Molecular Formula: C14H18O3
    5. Molecular Weight: 234.295
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 143815-07-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Benzene, 5-(1-cyclopenten-1-yl)-1,2,3-trimethoxy-(CAS DataBase Reference)
    10. NIST Chemistry Reference: Benzene, 5-(1-cyclopenten-1-yl)-1,2,3-trimethoxy-(143815-07-0)
    11. EPA Substance Registry System: Benzene, 5-(1-cyclopenten-1-yl)-1,2,3-trimethoxy-(143815-07-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 143815-07-0(Hazardous Substances Data)

143815-07-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 143815-07-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,8,1 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 143815-07:
(8*1)+(7*4)+(6*3)+(5*8)+(4*1)+(3*5)+(2*0)+(1*7)=120
120 % 10 = 0
So 143815-07-0 is a valid CAS Registry Number.

143815-07-0Relevant articles and documents

Synthesis and biological evaluation of cis-restrained carbocyclic combretastatin A-4 analogs: Influence of the ring size and saturation on cytotoxic properties

Nowikow, Christina,Fuerst, Rita,Kauderer, Maria,Dank, Christian,Schmid, Walther,Hajduch, Marian,Rehulka, Jiri,Gurska, Sona,Mokshyna, Olena,Polishchuk, Pavel,Zupkó, István,Dzubak, Petr,Rinner, Uwe

, (2019/08/12)

Combretastatin A-4 (CA-4) is a highly cytotoxic natural product and several derivatives have been prepared which underwent clinical trial. These investigations revealed that the cis-stilbene moiety of the natural product is prone to undergo cis/trans isomerization under physiological conditions, reducing the overall activity of the drug candidates. Herein, we report the preparation of cis-restrained carbocyclic analogs of CA-4. The compounds, which differ by the size and hybridization of the carbocyclic ring have been evaluated for their cytotoxic properties and their ability to inhibit tubulin polymerization. Biological data, supported by molecular docking studies, identified cyclobutenyl and cyclobutyl derivatives of the natural product as highly promising drug candidates.

PALLADIUM CATALYZED DOUBLE HECK ARYLATION OF CYCLOPENTENE

Prashad, Mahavir,Tomesch, John C.,Wareing, James R.,Smith, Howard C.,Cheon, Seung Hoon

, p. 2877 - 2880 (2007/10/02)

A convenient synthesis of 1,3-diarylcyclopentenes is described via a palladium catalyzed double Heck arylation of cyclopentene with aromatic halides.

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