1438263-90-1

Basic information

• Product Name: (S)-N-(4-bromobenzyl)-N,N,4-trimethyl-2-(1-methyl-3-(4-nitrophenyl)thioureido)-pentan-1-ammonium bromide
• Synonyms: (S)-N-(4-bromobenzyl)-N,N,4-trimethyl-2-(1-methyl-3-(4-nitrophenyl)thioureido)-pentan-1-ammonium bromide
• CAS NO: 1438263-90-1
• Molecular Weight: 588.407
• Mol File: 1438263-90-1.mol

Chemical Properties

• CAS DataBase Reference: (S)-N-(4-bromobenzyl)-N,N,4-trimethyl-2-(1-methyl-3-(4-nitrophenyl)thioureido)-pentan-1-ammonium bromide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-(4-bromobenzyl)-N,N,4-trimethyl-2-(1-methyl-3-(4-nitrophenyl)thioureido)-pentan-1-ammonium bromide(1438263-90-1)
• EPA Substance Registry System: (S)-N-(4-bromobenzyl)-N,N,4-trimethyl-2-(1-methyl-3-(4-nitrophenyl)thioureido)-pentan-1-ammonium bromide(1438263-90-1)

Safety Data

• Hazardous Substances Data: 1438263-90-1(Hazardous Substances Data)

Upstream product

• 589-15-1 1-bromomethyl-4-bromobenzene 
• 53363-89-6 N-t-butoxycarbonyl-N-methyl-L-leucine 

Relevant articles and documents

Novel bifunctional thiourea-ammonium salt catalysts derived from amino acids: Application to highly enantio- and diastereoselective aza-Henry reaction

The development of new efficient and easily accessible catalysts has been one of the focuses in asymmetric phase-transfer catalysis. In this paper, a novel class of chiral bifunctional thiourea-ammonium phase-transfer catalysts were synthesized from commercially available α-amino acids. The structural modularity of these catalysts permits facile tunings to achieve optimum results, which was demonstrated in catalyzing the aza-Henry reaction with excellent enantioselectivities (up to 99.5% ee) and diastereoselectivities (up to >25:1 dr).