1438432-27-9

Upstream product

• 627-37-2 N-methyl-N-allylamine 
• 2905-25-1 o-bromobenzenesulfonyl chloride 
• 98192-14-4 2-bromo-N-methylbenzenesulfonamide 
• 106-95-6 allyl bromide 
• 88-21-1 2-amino-1-benzenesulfonic acid 
• 576-92-1 bromobenzene-2-sulfonic acid 

Downstream Products

• 1438432-33-7 (2E)-4-{[(2-bromophenyl)sulfonyl](methyl)amino}-N-methoxy-N-methylbut-2-enamide 
• 1438432-34-8 2-bromo-N-methyl-N-[(2E)-3-phenylprop-2-en-1-yl]benzenesulfonamid 
• 1438432-41-7 2-(2-methyl-1,1-dioxido-3,4-dihydro-2H-1,2-benzothiazin-4-yl)-1-(4-tolyl)ethanone 
• 1438432-35-9 2-bromo-N-methyl-N-[(2E)-4-(phenylsulfanyl)but-2-en-1-yl]benzenesulfonamide 
• 1438432-30-4 2-bromo-N-methyl-N-[(2E)-4-oxopent-2-en-1-yl]benzenesulfonamide 
• 1438432-31-5 methyl (2E)-4-{[(2-bromophenyl)sulfonyl](methyl)amino}but-2-enoate 
• 1438432-32-6 2-bromo-N-methyl-N-[(2E)-4-(4-tolyl)-4-oxobut-2-en-1-yl]benzenesulfonamide 

Relevant academic research and scientific papers

Ligand free Pd catalyzed cyclization-influence of steric hindrance

Synthesis of sultams was performed using ligand free palladium catalyst following Heck cyclization. The diverse synthesized intermediates in this strategy includes halogenated sulfonyl chloride, alkyl/aryl sulfonamides, N-alkylation using halogenated alke

Merging cross-metathesis and radical cyclization: A straightforward access to 4-substituted benzosultams

N-Alkyl-N-allyl-2-bromobenzenesulfonamides were functionalized by selective E-cross-metathesis with various alkenes. Subsequent radical cyclization initiated by 2,2′-azobis(isobutyronitrile) and tris(trimethylsilyl)silane gave the corresponding 4-substituted benzosultams directly in moderate-to-good yields.