627-37-2

Basic information

• Product Name: N-Allylmethylamine
• Synonyms: 2-Propen-1-amine, N-methyl-;allylmethylamine;methylallylamine;N-Allyl-N-methylamine;n-methyl-2-propen-1-amin;n-methyl-2-propen-1-amine;n-methyl-allylamin;N-ALLYLMETHYLAMINE
• CAS NO: 627-37-2
• Molecular Formula: C₄H₉N
• Molecular Weight: 71.12
• EINECS: 210-996-0
• Mol File: 627-37-2.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 64-66 °C(lit.)
• Flash Point: −19 °F
• Appearance: colourless liquid,
• Density: 0.741 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.412(lit.)
• Storage Temp.: 2-8°C
• PKA: 9.88±0.10(Predicted)
• Water Solubility: Miscible with water.
• BRN: 1098387
• CAS DataBase Reference: N-Allylmethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Allylmethylamine(627-37-2)
• EPA Substance Registry System: N-Allylmethylamine(627-37-2)

Safety Data

• Hazard Codes: F,T
• Statements: 11-23/24/25-34
• Safety Statements: 26-36/37/39-45-37/39
• RIDADR: UN 3286 3/PG 2
• WGK Germany: 3
• RTECS: UC6632500
• F: 9-34
• HazardClass: 3
• PackingGroup: II
• Hazardous Substances Data: 627-37-2(Hazardous Substances Data)

Usage

Chemical Properties

Colorless to light yellow liqui

Uses

N-Allylmethylamine is used in the production of N-allyl-alfa,alfa-dichloro-N-methylacetamide. It is used as a functional monomer to coordinate with Cd(II)/Zn(II) ions to get the poly methyl methacrylate -butyl methacrylate - N-allylmethylamine (PMBA) films, which is useful as building blocks to fabricate a photo-catalytic cell.

InChI:InChI=1/C4H9N/c1-3-4-5-2/h3,5H,1,4H2,2H3

Upstream product

• 1476-23-9 allylisocyanate 
• 107-11-9 1-amino-2-propene 
• 74-88-4 methyl iodide 
• 89851-56-9 3-(allyl(methyl)amino)propanenitrile 
• 60-29-7 diethyl ether 
• 57-06-7 N-allyl isothiocyanate 
• 16250-37-6 N-allylformamide 
• 107-05-1 3-chloroprop-1-ene 
• 74-89-5 methylamine 
• 179404-69-4 N-methyl-N-allyltrifluoroacetamide 
• 57041-73-3 N-allyl-N-methyl-(bisdimethylamino) phosphoramide 
• 68003-55-4 benzylidene allylamine 
• 77-78-1 dimethyl sulfate 
• 106-95-6 allyl bromide 

Downstream Products

• 891861-84-0 N-methyl-2,4-dinitro-N-prop-2-en-1-ylaniline 
• 93-88-9 phenpromethamine 
• 67579-93-5 trans-N-methyl-N-allyl-1,2-cyclohexanediamine 
• 67198-25-8 trans-N,N'-dimethyl-N-allyl-1,2-cyclohexanediamine 
• 2155-94-4 N,N-dimethyl-2-propen-1-amine 
• 92243-73-7 (allylmethylamino)-phenyl-chloroborane 
• 872-50-4 1-methyl-pyrrolidin-2-one 
• 2687-90-3 N-methyl-N-allyl-formamide 
• 20240-70-4 N-allyl-N-methylhydrazine 
• 127144-18-7 N-allyl-2-amino-N-methyl-benzamide 
• 150630-79-8 N-Allyl-N-methyl-1-amino-2-propanone 

Relevant articles and documents

Highly enantioselective intramolecular cyclopropanation reactions of N-Allylic-N-methyldiazoacetamides catalyzed by chiral dirhodium(II) carboxamidates

Catalytic diazo decomposition of representative N-allylic-N- methyldiazoacetamides produced the corresponding intramolecular cyclopropanation products in good to excellent yields and with exceptional enantiocontrol. In the simplest case, with N-allyl-N-methyldiazoacetamide, catalysis by dirhodium(II) tetrakis[methyl 2-oxapyrrolidine-5(S)-carboxylate], Rh 2(5(S)-MEPY)4, achieved the highest yield and enantioselectivity (93% ee). Dirhodium(II) tetrakis[methyl 2-oxo-1-(3- phenylpropanoyl) imidazolidin-4(S)-carboxylate], Rh2(4S)-MPPIM) 4, was preferred for substituted N-allylic-N-methyldiazoacetamides from which 92-95% ee's were obtained in intramolecular cyclopropanation reactions (88-95% yields), even when the catalyst was employed in only 0.1 mol %. Competition with intramolecular dipolar cycloaddition was minimized with the use of Nmethyldiazoacetamides relative to N-tert-butyldiazoacetamides.

Synthesis of Mixed Secondary and Tertiary Amines

Abstract: A one-stage and facile method of synthesis of expensive methyl- and ethyl(allyl)amines, methyl- and ethyl(prop-2-ynyl)amines, and methyl- and ethyl(allyl)(3-phenylprop-2-ynyl)amines is developed. The synthesized amines present practical interest, because some (prop-2-ynyl)amines are used in the therapy cancer.

Synthesis and characterization of novel carbene complexes of phosphorus(V) fluorides with potential liquid-crystalline properties

A series of novel push-push I and push-pull II carbene-stabilized complexes of phosphorus(V) fluorides bearing substituents with liquid-crystalline properties were synthesized by the oxidative addition of difluoroamines to phosphorus(III) halides. These octahedral complexes were characterized by NMR spectroscopy and X-ray analysis.

Analine derivatives as OSC inhibitors

The present invention relates to compounds of formula (I) wherein U, Y, V, W, L, X, A1, A2, A3, A4, A5 and A6 are as defined in the description and claims and pharmaceutically acceptable salts and/or pharmaceutically acceptable esters thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia, hyperlipemia, arteriosclerosis, vascular diseases, mycoses, parasite infections, gallstones, tumors and/or hyperproliferative disorders, and/or treatment and/or prophylaxis of impaired glucose tolerance and diabetes.