14385-93-4

Basic information

• Product Name: 1,1'-Biphenyl, 2-iodo-4'-methyl-
• CAS NO: 14385-93-4
• Molecular Formula: C13H11I
• Molecular Weight: 294.135
• Mol File: 14385-93-4.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 1,1'-Biphenyl, 2-iodo-4'-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-Biphenyl, 2-iodo-4'-methyl-(14385-93-4)
• EPA Substance Registry System: 1,1'-Biphenyl, 2-iodo-4'-methyl-(14385-93-4)

Safety Data

• Hazardous Substances Data: 14385-93-4(Hazardous Substances Data)

Usage

Structure

1,1'-Biphenyl, 2-iodo-4'-methyl-

Explanation

Different sources of media describe the Explanation of 14385-93-4 differently. You can refer to the following data:
1. The structure refers to the arrangement of atoms in the molecule. This compound is a derivative of biphenyl, with a methyl group (CH3) attached to the 4' position and an iodine atom (I) at the 2 position.
2. The functional groups are specific parts of the molecule that determine its chemical reactivity. In this case, the aromatic ring is the core structure of biphenyl, the methyl group is a simple alkyl group, and the iodine atom is a halogen.
3. This compound is used as a building block for creating more complex organic molecules, particularly in the fields of organic synthesis and pharmaceutical research.
4. 1,1'-Biphenyl, 2-iodo-4'-methylis utilized in the production of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and materials.
5. The chemical properties of this compound make it a useful tool for researchers in the development of new drugs and materials, due to its reactivity and structural features.
6. It is important to handle 1,1'-Biphenyl, 2-iodo-4'-methylwith care, as it may pose certain health and environmental risks if not properly managed. This includes following safety protocols and guidelines to minimize exposure and contamination.

Functional Groups

Aromatic ring, methyl group, iodine atom

Application

Organic synthesis and pharmaceutical research

Usage

Production of pharmaceuticals and agrochemicals

Chemical Properties

Valuable tool in drug and material development

Safety Precautions

Potential health and environmental risks

Upstream product

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• 694-80-4 2-bromo-1-chlorobenzene 
• 106-38-7 para-bromotoluene 
• 139769-19-0 2-amino-4'-methylbiphenyl hydrochloride 
• 583-55-1 1-Bromo-2-iodobenzene 
• 197440-05-4 (4'-Methyl-biphenyl-2-yl)-pyrrolidin-1-yl-diazene 
• 70680-21-6 4-methyl-2'-nitrobiphenyl 
• 624-31-7 4-tolyl iodide 
• 552-16-9 ortho-nitrobenzoic acid 
• 1204-43-9 2-(4-methylphenyl)aniline 

Downstream Products

• 70680-23-8 2,4''''-Dimethyl-1:1',2':1'',3'':1''',2''':1''''-quinquephenyl 
• 148367-39-9 4--3-(trimethylsilyl)furan 
• 217-59-4 triphenylene 
• 1705-84-6 2-methyltriphenylene 
• 1430-97-3 2-methyl-9H-fluorene 
• 910612-13-4 9-(diphenylmethylene)-2-methyl-9H-fluorene 
• 114772-53-1 2-Cyano-4'-methylbiphenyl 
• 197440-06-5 2-Butyl-3-(2'-iodo-biphenyl-4-ylmethyl)-1,3-diaza-spiro[4.4]non-1-en-4-one 
• 138401-24-8 4'-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile 
• 876173-85-2 2,7-dibromo-2'-(4-tert-butylphenyl-1H-tetrazol-5-yl)-9,9'-spirobifluorene 
• 876173-84-1 2-bromo-2'-(4-tert-butylphenyl-1H-tetrazol-5-yl)-9,9'-spirobifluorene 
• 14684-10-7 5-(4-methyl-biphenyl-2-yl)-5H-5λ⁵-[5,5']spirobi(benzo[b]phosphindole) 
• 15001-77-1 5-(4'-methyl-biphenyl-2-yl)-5H-5λ⁵-[5,5']spirobi(benzo[b]phosphindole) 
• 3652-91-3 2-methyl-9H-carbazole 

Relevant articles and documents

Preferential oxidative addition in palladium(0)-catalyzed suzuki cross-coupling reactions of dihaloarenes with arylboronic acids

The study of Pd(0)-/t-Bu3P system as a powerful catalyst for the cross-coupling of n,m-dihaloarenes with 1 equiv of arylboronic acids is described. Our work demonstrated that the fate of the regenerated Pd(0) catalyst can be controlled when the appropriate ligand is employed. The results described here may lead to the development of new, efficient processes to conjugate polymers with controlled length which are potentially useful in molecular electronics. Copyright

Modular Tandem Mizoroki-Heck/Reductive Heck Reactions to Construct Fluorenes from Cyclic Diaryliodoniums

Starting from cyclic diaryliodoniums and terminal alkenes, a diverse set of fluorenes is conveniently constructed. The reactions catalyzed by palladium undergo one conventional Mizoroki-Heck reaction and one reductive Heck reaction. The scope of alkenes is general, leading to 29 fluorenes which would expand the structural diversity of fluorene reservoir. (Figure presented.).

Palladium-Catalyzed C-H Amination/[2 + 3] or [2 + 4] Cyclization via C(sp3or sp2)-H Activation

This report describes a palladium-catalyzed Catellani reaction consisting of amination/[2 + 3] or [2 + 4] cyclization via a carboxylate ligand-exchange strategy. This method effectively activates ortho-substituents that avoid a second C-H palladation. The scope of substrates was broad, o-methyl-substituted iodoarenes were applied to the reaction smoothly, and o-phenyl-substituted iodoarenes can also be obtained by this method. In terms of mechanism, density functional theory calculations proved the sequence of the key five-membered aryl-norbornene-palladacycle intermediate formation and C(sp3 or sp2)-H activation.

Synthesis of Fluorenes Starting from 2-Iodobiphenyls and CH2Br2 through Palladium-Catalyzed Dual C-C Bond Formation

A facile and efficient approach is developed for the synthesis of fluorene and its derivatives starting from 2-iodobiphenyls and CH2Br2. A range of fluorene derivatives can be synthesized under relatively mild conditions. The reaction proceeds via a tandem palladium-catalyzed dual C-C bond formation sequence through the key dibenzopalladacyclopentadiene intermediates, which are obtained from 2-iodobiphenyls through palladium-catalyzed C-H activation.