143945-65-7

Usage

Uses

Used in Pharmaceutical Industry:
2-Amino-5-bromo-4-fluorobenzoic acid is used as a chemical intermediate for the preparation of various complex organic compounds, particularly in the development of new pharmaceuticals. Its unique structure and functional groups enable it to be a key component in the synthesis of potential drug candidates, contributing to advancements in medicinal chemistry.
Used in Chemical Research:
In the field of chemical research, 2-Amino-5-bromo-4-fluorobenzoic acid is employed as a reagent or starting material for the synthesis of novel compounds. Its versatility in participating in different types of chemical reactions makes it a valuable tool for exploring new chemical pathways and discovering innovative applications in organic chemistry.

Upstream product

• 446-32-2 4-fluoroanthranilic acid 

Downstream Products

• 1204219-98-6 5-bromo-2-chloro-4-fluorobenzoic acid 
• 950577-02-3 C₈H₄BrFN₂O 

Relevant academic research and scientific papers

QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF

Disclosed are a series of quinolino-pyrrolidin-2-one compounds, and application thereof in preparation of drugs for ATM inhibitor-related diseases. The present disclosure specifically relates to a derivative compound represented by formula (I), tautomers thereof or pharmaceutically acceptable compositions thereof.

DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY

Provided herein are compounds of the Formula (I), (II), and (III), as well as pharmaceutically acceptable salts thereof, wherein the substituents are those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of oncologic diseases.

DEUTERATED BENZYLBENZENE DERIVATIVES AND METHODS OF USE

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions that are affected by SGLT inhibition.

1H-IMIDAZO[4,5-C]QUINOLINE DERIVATIVES IN THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES

The invention relates to the use of imidazoquinolines and salts thereof in the treatment of protein kinase diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases, imidazoquinolines for use in the treatment of protein kinase dependent diseases, a method of treatment against said diseases, comprising administering the imidazoquinolines to a warm-blooded animal, especially a human, pharmaceutical preparations comprising an imidazoquinoline, especially for the treatment of a protein kinase dependent disease, novel imidazoquinolines, and a process for the preparation of the novel imidazoquinolines.

1H-IMIDAZOQUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS

The invention relates to imidazoquinolines of formula (I) for use in the treatment of protein kinase dependent diseases; pharmaceutical preparations comprinsing an imidazoquinoline, especially for the treatment of a pretein kinase dependent disease; novel imidazoquinolines; and a process for the preparation of the novel imidazoquinilines.