143945-65-7

Basic information

• Product Name: 2-Amino-5-bromo-4-fluorobenzoicacid
• Synonyms: 2-Amino-5-bromo-4-fluorobenzoicacid;5-Bromo-4-fluoroanthranilic acid, 4-Bromo-2-carboxy-5-fluoroaniline;EOS-61436
• CAS NO: 143945-65-7
• Molecular Formula: C₇H₅BrFNO₂
• Molecular Weight: 234.0225032
• Mol File: 143945-65-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 215-217°C
• Boiling Point: 343.6±42.0 °C(Predicted)
• Appearance: /
• Density: 1.877±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 4.49±0.10(Predicted)
• CAS DataBase Reference: 2-Amino-5-bromo-4-fluorobenzoicacid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-5-bromo-4-fluorobenzoicacid(143945-65-7)
• EPA Substance Registry System: 2-Amino-5-bromo-4-fluorobenzoicacid(143945-65-7)

Safety Data

• Hazardous Substances Data: 143945-65-7(Hazardous Substances Data)

Usage

General Description

2-Amino-5-bromo-4-fluorobenzoic acid is a chemical compound with the molecular formula C7H5BrFNO2. 2-Amino-5-bromo-4-fluorobenzoicacid features a benzene ring as its core structure, which is substituted with amino, bromo, fluoro, and carboxylic acid functional groups. It belongs to the category of organobromides and organofluorides. With its aromatic ring and multiple functional groups, it can participate in different types of chemical reactions and bond formations. It is used as an intermediate in the preparation of various complex organic compounds, often in pharmaceutical and chemical research applications. Despite its practical utility in organic synthesis, like most chemicals, it should be handled with care as it may have varying levels of toxicity or hazards associated with its use or disposal.

Upstream product

• 446-32-2 4-fluoroanthranilic acid 

Downstream Products

• 1204219-98-6 5-bromo-2-chloro-4-fluorobenzoic acid 
• 950577-02-3 C₈H₄BrFN₂O 
• 853908-81-3 6-bromo-4-chloro-7-fluoro-3-nitroquinoline 
• 1656989-76-2 6-bromo-7-fluoro-3-nitroquinolin-4-ol 

Relevant articles and documents

QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF

Disclosed are a series of quinolino-pyrrolidin-2-one compounds, and application thereof in preparation of drugs for ATM inhibitor-related diseases. The present disclosure specifically relates to a derivative compound represented by formula (I), tautomers thereof or pharmaceutically acceptable compositions thereof.

DEUTERATED BENZYLBENZENE DERIVATIVES AND METHODS OF USE

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions that are affected by SGLT inhibition.

1H-IMIDAZOQUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS

The invention relates to imidazoquinolines of formula (I) for use in the treatment of protein kinase dependent diseases; pharmaceutical preparations comprinsing an imidazoquinoline, especially for the treatment of a pretein kinase dependent disease; novel imidazoquinolines; and a process for the preparation of the novel imidazoquinilines.