143946-48-9 Usage
Uses
Used in Pharmaceutical Industry:
4-Chloro-5-methylquinoline is used as an intermediate in the synthesis of various pharmaceuticals for its potential anti-inflammatory, anti-cancer, and anti-malarial properties. It serves as a building block in creating more complex organic compounds that can be utilized in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Chloro-5-methylquinoline is employed as a precursor in the production of various agrochemicals. Its role as an intermediate allows for the synthesis of compounds that can be used in pest control and crop protection, contributing to enhanced agricultural productivity.
Used in Chemical Research:
4-Chloro-5-methylquinoline is also utilized in chemical research as a model compound for studying the properties and reactions of quinoline derivatives. This helps in understanding the behavior of similar compounds and aids in the discovery of new applications and uses in various industries.
It is crucial to handle 4-chloro-5-methylquinoline with care due to its potential harmful effects if not properly managed. Safe handling practices are essential to ensure the safety of individuals and the environment during its use in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 143946-48-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,9,4 and 6 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 143946-48:
(8*1)+(7*4)+(6*3)+(5*9)+(4*4)+(3*6)+(2*4)+(1*8)=149
149 % 10 = 9
So 143946-48-9 is a valid CAS Registry Number.
143946-48-9Relevant academic research and scientific papers
Synthesis of ring-substituted 4-aminoquinolines and evaluation of their antimalarial activities
Madrid, Peter B.,Sherrill, John,Liou, Ally P.,Weisman, Jennifer L.,DeRisi, Joseph L.,Guy, R. Kiplin
, p. 1015 - 1018 (2007/10/03)
A simple two-step synthesis method was used to make 51 B-ring-substituted 4-hydroxyquinolines allowing analysis of the effect of ring substitutions on inhibition of growth of chloroquine sensitive and resistant strains of Plasmodium falciparum, the dominant cause of malaria morbidity. Substituted quinoline rings other than the 7-chloroquinoline ring found in chloroquine were found to have significant activity against the drug-resistant strain of P. falciparum W2.
Thioquinolone compounds which have useful pharmaceutical activity
-
, (2008/06/13)
Disclosed is a thioquinolone derivative which exhibits highly selective antibacterial activity against Helicobacter pylori.
