143949-42-2

Basic information

• Product Name: (6R,8S)-1-(phenylsulfonyl)-4-<(phenylsulfonyl)methyl>-1,6,7,8-tetrahydro-5,6,8-trimethylcyclopentindole
• Synonyms: (6R,8S)-1-(phenylsulfonyl)-4-<(phenylsulfonyl)methyl>-1,6,7,8-tetrahydro-5,6,8-trimethylcyclopentindole
• CAS NO: 143949-42-2
• Molecular Weight: 493.648
• Mol File: 143949-42-2.mol

Chemical Properties

• CAS DataBase Reference: (6R,8S)-1-(phenylsulfonyl)-4-<(phenylsulfonyl)methyl>-1,6,7,8-tetrahydro-5,6,8-trimethylcyclopentindole(CAS DataBase Reference)
• NIST Chemistry Reference: (6R,8S)-1-(phenylsulfonyl)-4-<(phenylsulfonyl)methyl>-1,6,7,8-tetrahydro-5,6,8-trimethylcyclopentindole(143949-42-2)
• EPA Substance Registry System: (6R,8S)-1-(phenylsulfonyl)-4-<(phenylsulfonyl)methyl>-1,6,7,8-tetrahydro-5,6,8-trimethylcyclopentindole(143949-42-2)

Safety Data

• Hazardous Substances Data: 143949-42-2(Hazardous Substances Data)

Upstream product

• 143949-38-6 ethyl (αξ,βξ)-α-<(1ξ,3S,5R)-3,5-dimethyl-2-methylenecyclopentyl>-β-hydroxy-α-methyl-1-(phenylsulfonyl)-1H-pyrrole-3-propanoate 
• 143949-39-7 ethyl (αξ)-α-<(1ξ,3S,5R)-3,5-dimethyl-2-methylenecyclopentyl>-α-methyl-β-oxo-1-(phenylsulfonyl)-1H-pyrrole-3-propanoate 
• 143949-40-0 3-<(2ξ)-2-<(1ξ,3S,5R)-3,5-dimethyl-2-methylenecyclopentyl>-1-oxo>propyl-1-(phenylsulfonyl)-1H-pyrrole 
• 88075-95-0 1-(phenylsulfonyl)-1H-pyrrole-3-carbaldehyde 
• 147484-85-3 (3R,5S)-2-[3-Benzenesulfonyl-2-(1-benzenesulfonyl-1H-pyrrol-3-yl)-2-hydroxy-1-methyl-propyl]-3,5-dimethyl-cyclopentanone 

Downstream Products

• 143949-46-6 (6R,8S)-4-<(E)-1-butenyl>1-(phenylsulfonyl)-1,6,7,8-tetrahydro-5,6,8-trimethylcyclopentindole 
• 143949-45-5 (6R,8S)-4-<(ξ)-2-butenyl>1-(phenylsulfonyl)-1,6,7,8-tetrahydro-5,6,8-trimethylcyclopentindole 
• 143949-44-4 (6R,8S)-4-(3-butenyl)-1-(phenylsulfonyl)-1,6,7,8-tetrahydro-5,6,8-trimethylcyclopentindole 
• 143949-43-3 (6R,8S)-4-ethyl-1-(phenylsulfonyl)-1,6,7,8-tetrahydro-5,6,8-trimethylcyclopentindole 

Relevant articles and documents

Preparation of alkyl-substituted indoles in the benzene portion. Part 11. Total synthesis of (6R,8S)-herbindole A, (6R,8S)-herbindole B, (6R,8S)-herbindole C (6R,8S)-cis-trikentrin A, (6R,8S)-cis-trikentrin B, (6R,8R)-trans-trikentrin B, and (6R,8R)-iso-t

The key intermediate, (3R,5S)-3,5-dimethyl-1-cyclopentenylmethanol (13) for chiral syntheses of herbindoles and trikentrins, was prepared from the known Diels-Alder adduct 12. Employing pertinent methodologies developed in the previous model study (preced

Total synthesis of (+)-herbindole A, (+)-herbindole B, and (+)-herbindole C. Determination of the absolute configuration of the natural herbindoles

(6R, 8S)-(+)-Herbindoles A (3a), B (3b), and C (3c) were synthesized from the chirality-definite Diels-Alder adduct 7 using an acid-induced indole cyclization reaction of 4 to 5, as well as novel reactions of the PhSO2 group of 24 with Mg in Me