143949-72-8 Usage
General Description
3-(1H-benzoimidazol-2-yl)-propionic acid hydrazide is a chemical compound with potential pharmaceutical applications. It belongs to the class of propionic acid derivatives and contains a benzoimidazole ring. 3-(1H-BENZOIMIDAZOL-2-YL)-PROPIONIC ACID HYDRAZIDE has been investigated for its potential as an antitumor agent and for its antioxidant properties. It may also have potential as a therapeutic agent for the treatment of neurological disorders due to its ability to cross the blood-brain barrier. Further research is needed to fully understand the pharmacological properties and potential uses of this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 143949-72-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,9,4 and 9 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 143949-72:
(8*1)+(7*4)+(6*3)+(5*9)+(4*4)+(3*9)+(2*7)+(1*2)=158
158 % 10 = 8
So 143949-72-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H12N4O/c11-14-10(15)6-5-9-12-7-3-1-2-4-8(7)13-9/h1-4H,5-6,11H2,(H,12,13)(H,14,15)
143949-72-8Relevant articles and documents
Synthesis of some hydroxamic acid derivatives of benzimidazole and their antibacterial and antifungal activities
Gunes,Cosar
, p. 1045 - 1048 (2007/10/02)
A number of 1H-benzimidazole-2-propanoic acid derivatives have been synthesized by Phillips method, and their antibacterial and antifungal activities have been tested. The chemical structures of the synthesized compounds were elucidated by spectroscopic (IR, NMR, mass) and elementary analysis. Investigation of antimicrobial activity of the compounds was done by agar dilution technique using bacteria (Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Mycobacterium smegmatis ATCC 607) and yeast-like fungi (Candida albicans, Candida tropicalis, Candida pseudotropicalis, Candida kruzei, Candida globrata). Among the compounds tested N-hydroxy-3-(1H-benzimidazol-2-yl)-propionamide (Compound 6) showed considerable activity against both Candida albicans and Candida tropicalis.
