14396-64-6

Basic information

• Product Name: 1,4-DIBROMO-2,3-EPOXYBUTANE
• Synonyms: 1,4-DIBROMO-2,3-EPOXYBUTANE
• CAS NO: 14396-64-6
• Molecular Formula: C₄H₆Br₂O
• Molecular Weight: 229.9
• Mol File: 14396-64-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 236.1°Cat760mmHg
• Flash Point: 92.1°C
• Appearance: /
• Density: 2.038g/cm³
• Vapor Pressure: 0.0739mmHg at 25°C
• Refractive Index: 1.545
• CAS DataBase Reference: 1,4-DIBROMO-2,3-EPOXYBUTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-DIBROMO-2,3-EPOXYBUTANE(14396-64-6)
• EPA Substance Registry System: 1,4-DIBROMO-2,3-EPOXYBUTANE(14396-64-6)

Safety Data

• Hazardous Substances Data: 14396-64-6(Hazardous Substances Data)

Usage

Physical state

Colorless, flammable liquid

Uses

a. Production of plastics
b. Biochemical reagent

Reactivity

Highly reactive alkylating agent

Interaction with biomolecules

Can react with nucleophilic sites in DNA, proteins, and other biomolecules

Potential health risks

a. Carcinogen (cancer-causing agent)
b. Mutagen (genetic mutation-inducing agent)

Exposure effects

a. Skin irritation
b. Eye irritation
c. Respiratory system irritation

Long-term exposure risks

Increased risk of cancer

Safety measures

Strict safety measures should be taken when handling and using this chemical

InChI:InChI=1/C4H6Br2O/c5-1-3-4(2-6)7-3/h3-4H,1-2H2

Upstream product

• 821-06-7 (E)-1,4-dibromobutene 
• 6974-12-5 1,4-dibromo-2-butene 

Downstream Products

• 138467-44-4 ethyl 6-bromo-4,5-epoxy-2-ethoxycarbonyl-2-(3'-phenyl-2'-propenyl)hexanoate 

Relevant articles and documents

FLUORODIOXOLANE-CONTAINING ALKYNES

Novel fluorinated dioxolane-containing alkyne compounds 1 and 2 were synthesized from hexafluoroacetone and either 1,4-dibromo-2-butene or propargyl alcohol.

NOVEL AMIDE DERIVATIVES

This invention relates to compounds which are represented by the general formula [I] ???[in which A stands for a group of the following formula [ao] or [b0] ???Ar1, Ar2 and Ar3 stand for optionally substituted phenyl; k stands for 0 or 1; m, n and s stand for 0, 1 or 2; R1 stands for hydrogen or optionally substituted lower alkyl; R2, R3, R4 and R5 either stand for hydrogen or optionally substituted lower alkyl, or R2 and R3, or R4 and R5 together stand for trimethylene and the like; R60 stands for hydrogen, alkyl, or the like; R61and R71 either stand for alkyl and the like, or together stand for trimethylene and the like; X stands for carbonyl or methylene; Y stands for nitrogen or methine; and Q- stands for anion], and the like. The compounds of the invention exhibit selective antagonism to muscarinic M3 receptors, and therefore are useful as safe and effective agents showing little side effect, for treating diseases of the respiratory, urinary and digestive systems.

Studies on the Synthesis of Ginkgolides. Rapid Construction of the Spirononane A and B Rings

The functionalised spirononane 30 is available from tert-butylcyclopentadiene 16 via spiroalkylation with 12b to give 17/18, followed by singlet oxygenation/aldolisation to the mixture of 21, 22, 25 and 26.Oxidation of the mixture gave two enediones