14396-65-7

Basic information

• Product Name: 1,4-Dibromo-2,3-butanediol
• Synonyms: DL-1,4-DIBROMO-2,3-BUTANEDIOL;1,4-DIBROMO-2,3-BUTANDIOL;1,4-DIBROMO-2,3-BUTANEDIOI;1,4-Dibromo-2,3-butanediol;1,4-DibroMo-2,3-butanediol;1,4-DibroMo-2,3-butanediol 95%;1,4-Dibromobutane-2,3-diol
• CAS NO: 14396-65-7
• Molecular Formula: C₄H₈Br₂O₂
• Molecular Weight: 247.91
• Product Categories: Organic Building Blocks;Oxygen Compounds;Polyols
• Mol File: 14396-65-7.mol
• Article Data: 2

Chemical Properties

• Melting Point: 82-84 °C(lit.)
• Boiling Point: 365.3 °C at 760 mmHg
• Flash Point: 174.7 °C
• Appearance: /
• Density: 2.124 g/cm³
• Vapor Pressure: 8.09E-07mmHg at 25°C
• Refractive Index: 1.583
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 12.49±0.20(Predicted)
• CAS DataBase Reference: 1,4-Dibromo-2,3-butanediol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dibromo-2,3-butanediol(14396-65-7)
• EPA Substance Registry System: 1,4-Dibromo-2,3-butanediol(14396-65-7)

Safety Data

• Hazard Codes: Xi
• Statements: 37/38-41
• Safety Statements: 26-39
• WGK Germany: 3
• Hazardous Substances Data: 14396-65-7(Hazardous Substances Data)

Usage

Uses

1,4-Dibromo-2,3-butanediol has been used in the preparation of diquaternary gemini surfactants.

General Description

1,4-Dibromo-2,3-butanediol reacts with aqueous alkaline sodium arsenite to yield mixture of DL-2,3,4-trihydroxybutylarsonic acid and DL-2,3-dihydroxybutane-1,4-bis(arsonic acid).

InChI:InChI=1/C4H8Br2O2/c5-1-3(7)4(8)2-6/h3-4,7-8H,1-2H2

Upstream product

• 299-70-7 threo-1,4-dibromo-2,3-butanediol 
• 329-15-7 4-trifluoromethyl-phenyl acetyl chloride 
• 564-00-1 (R,R)-butane-1,2:3,4-bisoxide 
• 2418-52-2 D-threitol 
• 110-14-5 butanediamide 

Downstream Products

• 1947-62-2 treosulfan 

Relevant articles and documents

Pharmaceutical intermediate 1,4-dibromo-2,3-butanediol synthesis method

The invention relates to a pharmaceutical intermediate 1,4-dibromo-2,3-butanediol synthesis method, which mainly comprises: adding 2 mol 1,4-diaminobutanedione and 4-6 mol 2-pyrrolidone to a reactioncontainer, reducing the solution temperature to 5-7 DEG C, adding 2-3 mol bismuth subcarbonate and 4-6 mol bromide hydrogen solution, maintaining for 30-60 min, continuously reducing the temperature to 1-3 DEG C, controlling the stirring speed at 170-190 rpm, maintaining for 40-60 min, standing for 30-50 min, precipitating the solid, washing the filtrate by using a methyl butyrate solution, washing with an octanenitrile solution, re-crystallizing in a cyclohexanone solution, precipitating the crystal, and dehydrating with a dehydrating agent to obtain the finished product 1,4-dibromo-2,3-butanediol.