14398-40-4

Upstream product

• 56013-05-9 (RS)-(E)-2-methyl-4-(2',6',6'-trimethyl-1'-cyclohexenyl)-3-butenal 
• 593-71-5 Chloroiodomethane 
• 79-77-6 (E)-β-ionone 
• 96-34-4 methyl chloroacetate 
• 58689-13-7 2-Methyl-2-[2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethenyl]oxirane 

Downstream Products

• 53210-15-4 4-(2,6,6-Trimethyl-1-cyclohexen-1-yl)-2-methyl-1-phenyl-trans-2-buten 
• 50895-68-6 2Z,7E-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,7-nonadiene-4-yne-1,6-diol 
• 50895-69-7 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)nona-2E,7E-dien-4-yne-1,6-diol 
• 154307-87-6 (Z)-1,3,3-trimethyl-2-(3-methylpent-2-en-4-ynyl)cyclohex-1-ene 
• 55497-47-7 (e)-3-methyl-2-(2',6',6'-trimethylcyclohexenyl)-penta-1,3-diene 
• 154307-85-4 (2E,7E)-9-(tert-Butyl-dimethyl-silanyloxy)-3,7-dimethyl-1-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,7-dien-5-yn-4-ol 
• 83587-49-9 C₂₄H₃₈NOPS 
• 83587-49-9 C₂₄H₃₈NOPS 
• 174834-02-7 2-((E)-5,5-Dibromo-3-methyl-penta-2,4-dienyl)-1,3,3-trimethyl-cyclohexene 
• 174833-99-9 3,7-dimethyl-1-(2,6,6-trimethyl-cyclohex-1-enyl)-octa-2,7-dien-5-yn-4-ol 
• 188965-82-4 (E)-2-Methyl-1-(3-methyl-1,1-dioxo-2,5-dihydro-1H-1λ⁶-thiophen-2-yl)-4-(2,6,6-trimethyl-cyclohex-1-enyl)-but-2-en-1-ol 
• 319926-96-0 (2E,7Z)-8-{[1,3]-dioxolan-2-yl}-3,7-dimethyl-1-(2,6,6-trimethylcyclohex-1-en-1-yl)octa-2,7-dien-5-yn-4-ol 
• 199007-99-3 (2E,7Z)-9-(tert-Butyl-dimethyl-silanyloxy)-3,7-dimethyl-1-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,7-dien-5-yn-4-ol 
• 256518-38-4 (1E,3E)-2-methyl-1-[(trifluoromethanesulfonyl)oxy]-4-(2,6,6-trimethylcyclohex-1-en-1-yl)buta-1,3-diene 

Relevant academic research and scientific papers

Efficient Access to All-Carbon Quaternary and Tertiary α-Functionalized Homoallyl-type Aldehydes from Ketones

β,γ-Unsaturated aldehydes with all-carbon quaternary or tertiary α-centers were rapidly assembled from ketones through a unique synthetic operation consisting of 1) C1 homologation, 2) Lewis acid mediated epoxide–aldehyde isomerization, and 3) electrophilic trapping. The synthetic equivalence of a vinyl oxirane and a β,γ-unsaturated aldehyde is the key concept of this previously undisclosed tactic. Mechanistic studies and labeling experiments suggest that an aldehyde enolate is a crucial intermediate. The homologating carbenoid formation plays a critical role in determining the chemoselectivity.

Process for the preparation of glycidic ester and an aldehyde

The invention relates to a process comprising a condensation step wherein a starting aldehyde or ketone is made to react with an ester of an ±-haloacid to form a glycidic ester, whereby the reaction is carried out in the presence of a dipolar aprotic comp

Phosphonate reagent compositions

Novel phosphonate compounds of the formula STR1 are disclosed and claimed, as well as methods for manufacturing the phosphonates from C-14 through C-16 aldehydes. The phosphonate compounds of the present invention can be employed to form 13-cis retinoic acid, retin-A and beta-carotene.

175. The Synthesis of β,γ- and α,β-Unsaturated Aldehydes via Polyene Epoxides

A substitute for the Darzens glycidic ester synthesis for converting unsaturated ketones or aldehydes into the homologated β,γ- or α,β-unsaturated aldehydes employing sulfur ylides is desribed.The carbonyl group is converted into the unsaturated oxirane which is then rearranged to the new aldehyde.High yields of isomerically pure aldehydes are available by this method and the process is of practical importance in the conversion of β-ionone into the β-C14-aldehyde, a key intermediate in the Isler synthesis of vitamin A.The efficient preparation of α- and β-cyclocitral by the novel process is also described.

Process for preparing epoxide-cyclohexyl compound and resultant compound

Homologation of α,β-polyene unsaturated aldehydes and ketones to form α,β-unsaturated aldehydes via epoxidation of the ketone or aldehyde and intermediates in this process such as β,γ-unsaturated polyene aldehydes.