14401-10-6

Basic information

• Product Name: N-EPSILON-2,4-DNP-L-LYSINE HYDROCHLORIDE
• Synonyms: NEPSILON-DNP-L-LYSINE HYDROCHLORIDE;N-EPSILON-2,4-DNP-L-LYSINE HYDROCHLORIDE;NEPSILON-(2,4-DINITROPHENYL)-L-LYSINE HYDROCHLORIDE;EPSILON-2 4-DINITROPHENYL-L-LYSINE HYDROCHLORIDE;EPSILON-DNP-L-LYSINE HYDROCHLORIDE;?-DNP-L-Lysine hydrochloride ?-2,4-Dinitrophenyl-L-lysine hydrochloride;Dinitrophenyllysinehydrochloride;N^(epsilum)-(2,4-Dinitrophenyl)-L-lysine hydrochloride
• CAS NO: 14401-10-6
• Molecular Formula: C₁₂H₁₆N₄O₆*ClH
• Molecular Weight: 348.74
• EINECS: 238-366-0
• Product Categories: Substrates;DNP-Amino Acids;Amino Acids;Amino Acids (N-Protected);Biochemistry
• Mol File: 14401-10-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 571.6°Cat760mmHg
• Flash Point: 299.5°C
• Appearance: /
• Density: 1.46g/cm³
• Vapor Pressure: 6.6E-14mmHg at 25°C
• Refractive Index: 19 ° (C=2, MeOH)
• Storage Temp.: −20°C
• CAS DataBase Reference: N-EPSILON-2,4-DNP-L-LYSINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-EPSILON-2,4-DNP-L-LYSINE HYDROCHLORIDE(14401-10-6)
• EPA Substance Registry System: N-EPSILON-2,4-DNP-L-LYSINE HYDROCHLORIDE(14401-10-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 14401-10-6(Hazardous Substances Data)

Usage

Description

N-Epsilon-2,4-DNP-L-lysine hydrochloride, a derivative of the essential amino acid lysine, is a chemical compound characterized by the presence of a di-nitrophenyl group. It is widely utilized in the fields of biochemistry and molecular biology for its unique properties and applications.
Used in Biochemistry and Molecular Biology Research:
N-Epsilon-2,4-DNP-L-lysine hydrochloride is used as a substrate for enzymes such as transglutaminases, which are involved in protein cross-linking and modification. N-EPSILON-2,4-DNP-L-LYSINE HYDROCHLORIDE serves as a valuable tool for studying enzyme kinetics and protein-protein interactions in various biological systems.
Used in Enzyme Kinetics Studies:
N-Epsilon-2,4-DNP-L-lysine hydrochloride is employed as a substrate to investigate the activity and specificity of transglutaminase enzymes. By monitoring the reaction rates and product formation, researchers can gain insights into the enzyme's catalytic mechanism and its role in biological processes.
Used in Protein-Protein Interaction Analysis:
N-EPSILON-2,4-DNP-L-LYSINE HYDROCHLORIDE is used to explore the interactions between proteins in different biological systems. By incorporating N-Epsilon-2,4-DNP-L-lysine hydrochloride into proteins, researchers can study the effects of protein cross-linking on protein-protein interactions and their implications in cellular functions.
Used in Drug Development:
N-Epsilon-2,4-DNP-L-lysine hydrochloride may also be used in the development of drugs targeting transglutaminase enzymes. By understanding the enzyme's interaction with this compound, researchers can design inhibitors or activators to modulate the enzyme's activity for therapeutic purposes.
It is crucial to handle N-Epsilon-2,4-DNP-L-lysine hydrochloride with care, as it can be hazardous if not used properly. Proper safety measures and guidelines should be followed to ensure the safe use of this chemical compound in research and development.

InChI:InChI=1/C12H16N4O6/c13-9(12(17)18)3-1-2-6-14-10-5-4-8(15(19)20)7-11(10)16(21)22/h4-5,7,9,14H,1-3,6,13H2,(H,17,18)

Downstream Products

• 439680-85-0 methyl (S)-2-[[[(3,5,6-trichloro-2-pyridyl)oxy]methylcarbonyl]amino]-6-(2,4-dinitrophenyl)aminohexanoate 
• 1202639-01-7 C₂₂H₂₆N₄O₁₀S 
• 5535-52-4 tolyl vinyl sulfone 
• 1094-76-4 N⁶-(2,4-dinitro-phenyl)-L-lysine 
• 10466-73-6 methyl (S)-2-amino-6-(2,4-dinitrophenyl)aminohexanoate