144015-76-9

Upstream product

• 143955-40-2 (4S)-3-<(2R,3S,4S)-3-Hydroxy-2-methyl-4-phenylsulfanyl-1-oxoheptyl>-4-(1-methylethyl)-1,3-oxazolidin-2-one 
• 143879-15-6 (α-phenylthio)valeraldehyde 
• 882-33-7 diphenyldisulfane 
• 931-59-9 benzenesulfenyl chloride 

Relevant academic research and scientific papers

Kinetic resolution in asymmetric anti aldol reactions of branched and straight chain racemic 2-phenylsulfanyl aldehydes: Asymmetric synthesis of cyclic ethers and lactones by phenylsulfanyl migration

The kinetic resolution of branched and straight chain 2-phenylsulfanyl aldehydes by the Lewis acid-catalysed asymmetric anti aldol reaction followed by reduction to single enantiomers of 1,3-diols and/or acid-catalysed cyclisation with PhS migration provides a route to enantiomerically pure cyclic ethers and lactones with full stereochemical control.

Kinetic resolutions in anti aldol reactions with racemic 2-phenylthio aldehydes: Asymmetric synthesis of cyclic ethers and lactones with phenylthio migration

Kinetic resolutions in Lewis acid catalysed asymmetric anti aldol reactions of the boron enolate of imide (2) with racemic 2-phenylthio aldehydes (3a) - (3c) give good yields of anti,anti aldols (7). Synthesis of homochiral cyclic ethers (4a) - (4c) and (