143955-40-2Relevant academic research and scientific papers
Kinetic resolution in asymmetric anti aldol reactions of branched and straight chain racemic 2-phenylsulfanyl aldehydes: Asymmetric synthesis of cyclic ethers and lactones by phenylsulfanyl migration
Chibale, Kelly,Warren, Stuart
, p. 1935 - 1940 (2007/10/03)
The kinetic resolution of branched and straight chain 2-phenylsulfanyl aldehydes by the Lewis acid-catalysed asymmetric anti aldol reaction followed by reduction to single enantiomers of 1,3-diols and/or acid-catalysed cyclisation with PhS migration provides a route to enantiomerically pure cyclic ethers and lactones with full stereochemical control.
KINETIC RESOLUTIONS IN ANTI ALDOL REACTIONS: ASYMMETRIC SYNTHESIS OF HETEROCYCLES WITH PHENYLTHIO MIGRATION
Chibale, Kelly,Warren, Stuart
, p. 401 - 402 (2007/10/02)
Kinetic resolutions in Lewis acid catalysed asymmetric anti aldol reactions of the boron enolate of imide (2) with racemic 2-phenylthio aldehydes (3) give good yields of Felkin anti,anti aldols (6).The synthesis of homochiral cyclic ethers (4) and a simple novel route to homochiral lactones (5) are described.
Kinetic resolutions in anti aldol reactions with racemic 2-phenylthio aldehydes: Asymmetric synthesis of cyclic ethers and lactones with phenylthio migration
Chibale,Warren
, p. 4369 - 4372 (2007/10/02)
Kinetic resolutions in Lewis acid catalysed asymmetric anti aldol reactions of the boron enolate of imide (2) with racemic 2-phenylthio aldehydes (3a) - (3c) give good yields of anti,anti aldols (7). Synthesis of homochiral cyclic ethers (4a) - (4c) and (
