144016-18-2

Upstream product

• 147484-85-3 (3R,5S)-2-[3-Benzenesulfonyl-2-(1-benzenesulfonyl-1H-pyrrol-3-yl)-2-hydroxy-1-methyl-propyl]-3,5-dimethyl-cyclopentanone 
• 3112-85-4 methylphenylsulfonate 
• 143949-41-1 (αξ)-α-<(1ξ)-1-<(1ξ,3S,5R)-3,5-dimethyl-2-methylenecyclopentyl>ethyl>-1-(phenylsulfonyl)-α-<(phenylsulfonyl)methyl>-1H-pyrrole-3-methanol 
• 143949-38-6 ethyl (αξ,βξ)-α-<(1ξ,3S,5R)-3,5-dimethyl-2-methylenecyclopentyl>-β-hydroxy-α-methyl-1-(phenylsulfonyl)-1H-pyrrole-3-propanoate 
• 143949-39-7 ethyl (αξ)-α-<(1ξ,3S,5R)-3,5-dimethyl-2-methylenecyclopentyl>-α-methyl-β-oxo-1-(phenylsulfonyl)-1H-pyrrole-3-propanoate 
• 143949-40-0 3-<(2ξ)-2-<(1ξ,3S,5R)-3,5-dimethyl-2-methylenecyclopentyl>-1-oxo>propyl-1-(phenylsulfonyl)-1H-pyrrole 
• 88075-95-0 1-(phenylsulfonyl)-1H-pyrrole-3-carbaldehyde 

Relevant academic research and scientific papers

Preparation of alkyl-substituted indoles in the benzene portion. Part 11. Total synthesis of (6R,8S)-herbindole A, (6R,8S)-herbindole B, (6R,8S)-herbindole C (6R,8S)-cis-trikentrin A, (6R,8S)-cis-trikentrin B, (6R,8R)-trans-trikentrin B, and (6R,8R)-iso-t

The key intermediate, (3R,5S)-3,5-dimethyl-1-cyclopentenylmethanol (13) for chiral syntheses of herbindoles and trikentrins, was prepared from the known Diels-Alder adduct 12. Employing pertinent methodologies developed in the previous model study (preced

Total synthesis of (+)-herbindole A, (+)-herbindole B, and (+)-herbindole C. Determination of the absolute configuration of the natural herbindoles

(6R, 8S)-(+)-Herbindoles A (3a), B (3b), and C (3c) were synthesized from the chirality-definite Diels-Alder adduct 7 using an acid-induced indole cyclization reaction of 4 to 5, as well as novel reactions of the PhSO2 group of 24 with Mg in Me