144034-41-3

Upstream product

• 124-68-5 2-Amino-2-methyl-1-propanol 
• 7169-06-4 2,3-dimethoxybenzoyl chloride 
• 1521-38-6 2,3-dimethoxybenzoic acid 

Downstream Products

• 412297-44-0 3-methoxy-2-[2]naphthyl-benzoic acid 
• 558441-39-7 4,5-dihydro-2-[3'-methoxy-2'-(naphthalen-2-yl)phenyl]-4,4-dimethyloxazole 
• 558441-31-9 2,2-diphenyl-2H,7H-benzo[7,8]fluoreno[4,3-b]pyran-7-one 
• 57598-39-7 2-<2-(2-Methoxyphenyl)-3-methoxyphenyl>-4,4-dimethyl-2-oxazoline 
• 87306-84-1 2',6-dimethoxy-(1,1'-biphenyl)-2-carboxaldehyde 
• 57598-50-2 2-butyl-3-methoxybenzoic acid 
• 57598-41-1 2-(2'-butyl-3'-methoxyphenyl)-4,4-dimethyl-4,5-dihydrooxazole 
• 244608-07-9 3,5-Bis-benzyloxy-4-[1-(2-benzyloxycarbonyl-6-methoxy-phenyl)-vinyl]-benzoic acid benzyl ester 
• 244608-10-4 3-Benzyloxy-4-iodo-5-(3-methoxy-2-vinyl-benzoyloxy)-benzoic acid benzyl ester 
• 244608-12-6 1-benzyloxy-10-methoxy-11-methylene-6-oxo-6,11-dihydro-dibenzo[b,e]oxepine-3-carboxylic acid benzyl ester 
• 302836-70-0 2-[1-(3-benzyloxyphenyl)vinyl]-3-methoxybenzoic acid benzyl ester 
• 244608-09-1 3-methoxy-2-vinylbenzoic acid 3-benzyloxy-2-iodophenyl ester 

Relevant academic research and scientific papers

Structural interrogation of benzosuberene-based inhibitors of tubulin polymerization

The discovery of 3-methoxy-9-(3′,4′,5′-trimethoxyphenyl)-6,7-dihydro-5H-benzo[7]annulen-4-ol (a benzosuberene-based analogue referred to as KGP18) was originally inspired by the natural products colchicine and combretastatin A-4 (CA4). The relative struct

Synthesis of antimicrobial natural products targeting FtsZ: (+)-totarol and related totarane diterpenes

(Equation Presented). An efficient, convergent synthesis of totarol by a diastereoselective epoxide/alkene/arene bicyclization is described. The reported synthesis enables the preparation of related diterpenes totaradiol and totarolone as well as previously unavailable derivatives that exhibit comparable inhibition of the bacterial cell division protein FtsZ.

Photochromic properties of new benzoindene-fused 2H-chromenes

The synthesis and the photochromic properties of new photochromic 6,7- and 7,8-benzoindene annellated benzopyrans are described. When compared to parent indeno-fused 2H-chromenes (2H-[1]benzopyrans), compounds 10 and 12 exhibit a significant bathochromic shift of maximum-absorption wavelength, an increase in the colorability, and similar fading rates.

Application of an intramolecular heck reaction for the construction of the balanol aryl core structure

The highly functionalized aryl core structure of balanol has been synthesized employing a regioselective intramolecular Heck reaction as the key step. This approach can potentially lead to new types of analogues of the potent PKC inhibitor.