144043-20-9

Basic information

• Product Name: (S)-3-DIMETHYLAMINOPYRROLIDINE 2HCL
• Synonyms: (3S)-N,N-dimethylpyrrolidin-3-amine dihydrochloride;(S)-N,N-Dimethyl-3-pyrrolidinamine Dihydrochloride;(3S)-N,N-Dimethylpyrrolidin-3-amine hydrochloride;(S)-N,N-Dimethyl-3-pyrrolidinamine Dihydrochloride,99%e.e.;(S)-3-DIMETHYLAMINOPYRROLIDINE 2HCL;(S)-(-)-3-Dimethylaminopyrroli;(S)-N,N-diMethylpyrrolidin-3-aMine dihydrochloride;S- N,N-diMethyl-3-PyrrolidinaMine.2HCl
• CAS NO: 144043-20-9
• Molecular Formula: C₆H₁₄N₂*2ClH
• Molecular Weight: 187.11
• Mol File: 144043-20-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 176-181℃
• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive: Hygroscopic
• CAS DataBase Reference: (S)-3-DIMETHYLAMINOPYRROLIDINE 2HCL(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-DIMETHYLAMINOPYRROLIDINE 2HCL(144043-20-9)
• EPA Substance Registry System: (S)-3-DIMETHYLAMINOPYRROLIDINE 2HCL(144043-20-9)

Safety Data

• Hazardous Substances Data: 144043-20-9(Hazardous Substances Data)

Usage

Description

(S)-3-Dimethylaminopyrrolidine 2HCl is a chemical compound characterized by a pyrrolidine ring with a dimethylamine group attached to it, existing in the form of a hydrochloride salt. This chiral compound is significant in the field of organic chemistry due to its versatile applications in synthesis, catalysis, and as a precursor in various industries.

Uses

Used in Organic Synthesis:
(S)-3-Dimethylaminopyrrolidine 2HCl is used as a reagent for the formation of chiral compounds, which are essential in creating enantiomerically pure substances that can exhibit different biological activities.
Used as a Catalyst:
In various chemical reactions, (S)-3-Dimethylaminopyrrolidine 2HCl serves as a catalyst to enhance the rate of reactions, making it a valuable tool in improving the efficiency of chemical processes.
Used in Pharmaceutical Synthesis:
As a precursor, (S)-3-Dimethylaminopyrrolidine 2HCl is utilized in the synthesis of pharmaceuticals, contributing to the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Synthesis:
Similarly, in the agrochemical industry, this compound is used as a precursor in the synthesis of various agrochemicals, aiding in the production of substances that can protect crops and enhance agricultural productivity.
Used in Research:
(S)-3-Dimethylaminopyrrolidine 2HCl has potential applications in research areas such as medicinal chemistry, where it can be employed to study the properties and interactions of chiral compounds, and materials science, where it may contribute to the development of new materials with specific properties.
Overall, (S)-3-Dimethylaminopyrrolidine 2HCl is a multifaceted chemical with a wide range of applications across different industries, making it an important component in the advancement of organic chemistry and related fields.

InChI:InChI=1/C6H14N2.2ClH/c1-8(2)6-3-4-7-5-6;;/h6-7H,3-5H2,1-2H3;2*1H/t6-;;/m0../s1

Upstream product

• 69478-77-9 ((S)-1-Benzyl-pyrrolidin-3-yl)-dimethyl-amine 
• 69478-77-9 ((R)-1-benzylpyrrolidin-3-yl)dimethylamine 

Downstream Products

• 1421372-06-6 N-{5-chloro-(4-pyrazolo[1,5-a]pyridin-3-yl)-pyrimidin-2-yl}-4-[(3R)-3-dimethylaminopyrrolidin-1-yl]-6-methoxybenzene-1,3-diamine 
• 1421373-41-2 N-[5-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-2-[(3R)-3-dimethylaminopyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide 
• 1258943-41-7 (+/-)-[1-(2-bromophenyl)pyrrolidin-3-yl]dimethylamine 
• 1258943-42-8 (+/-)-[1-(2-iodophenyl)pyrrolidin-3-yl]dimethylamine 

Relevant articles and documents

Optically active 1,4-dihydropyridine compounds as bradykinin antagonists

This invention provides a compound of the formula (I): and its pharmaceutically acceptable salts, wherein A1 and A2 are each halo; R1 and R2 are independently C1-4 alkyl; R3 is substituted or unsubstituted, phenyl or naphthyl; Y is heterocyclic group sele