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1440510-02-0

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1440510-02-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1440510-02-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,0,5,1 and 0 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1440510-02:
(9*1)+(8*4)+(7*4)+(6*0)+(5*5)+(4*1)+(3*0)+(2*0)+(1*2)=100
100 % 10 = 0
So 1440510-02-0 is a valid CAS Registry Number.

1440510-02-0Relevant articles and documents

NON-RIBOSE CONTAINING INHIBITORS OF HISTONE METHYLTRANSFERASE DOT1L FOR CANCER TREATMENT

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Paragraph 0062; 0063; 00118, (2015/02/19)

A compound of Formula I, a pharmaceutically acceptable salt thereof, a prodrug thereof, or combinations thereof: wherein R1 is H, methyl, or benzyl: R2 is 2-cyanoethyl, 2-methoxycarbonylethyl, or 2-iodoethyl; X is N or S; wherein if

Synthesis, activity and metabolic stability of non-ribose containing inhibitors of histone methyltransferase DOT1L

Deng, Lisheng,Zhang, Li,Yao, Yuan,Wang, Cong,Redell, Michele S.,Dong, Shuo,Song, Yongcheng

, p. 822 - 826 (2013/08/26)

Histone methyltransferase DOT1L is a drug target for MLL leukemia. We report an efficient synthesis of a cyclopentane-containing compound that potently and selectively inhibits DOT1L (Ki = 1.1 nM) as well as H3K79 methylation (IC50 ~

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