1440513-46-1Relevant articles and documents
Iron-catalyzed C-C bond formation via cross dehydrative coupling reaction of N-heterocyclic aminols with electron rich arenes: Facile access to C4-aryl-dihydroquinazolines
Arun Kumar,Srinivasulu,Saidulu,Santhosh Kumar,Sridhar,Rajender Reddy
, p. 794 - 802 (2016)
The direct coupling of sp3 C-OH bond of N-heterocyclic aminols with sp2 C-H bond of electron rich arenes have been achieved via iron catalyzed dehydrative cross coupling strategy. This novel protocol provides an efficient and straight forward route to access biologically important C4-aryl-3,4-dihydroquinazoline derivatives through the reaction of C4-hydroxy-3,4-dihydroquinazoline/aminol with phenol and aniline derivatives under mild reaction conditions.