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1-tert-butyl 3-(2,3,4-trifluorobenzyl) 2-methylmalonate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1440524-48-0 Structure
  • Basic information

    1. Product Name: 1-tert-butyl 3-(2,3,4-trifluorobenzyl) 2-methylmalonate
    2. Synonyms: 1-tert-butyl 3-(2,3,4-trifluorobenzyl) 2-methylmalonate
    3. CAS NO:1440524-48-0
    4. Molecular Formula:
    5. Molecular Weight: 318.293
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1440524-48-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-tert-butyl 3-(2,3,4-trifluorobenzyl) 2-methylmalonate(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-tert-butyl 3-(2,3,4-trifluorobenzyl) 2-methylmalonate(1440524-48-0)
    11. EPA Substance Registry System: 1-tert-butyl 3-(2,3,4-trifluorobenzyl) 2-methylmalonate(1440524-48-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1440524-48-0(Hazardous Substances Data)

1440524-48-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1440524-48-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,0,5,2 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1440524-48:
(9*1)+(8*4)+(7*4)+(6*0)+(5*5)+(4*2)+(3*4)+(2*4)+(1*8)=130
130 % 10 = 0
So 1440524-48-0 is a valid CAS Registry Number.

1440524-48-0Relevant articles and documents

Enantioselective phase-transfer catalytic α-alkylation of 2-methylbenzyl tert-butyl malonates

Ha, Min Woo,Hong, Suckchang,Park, Cheonhyoung,Park, Yohan,Lee, Jihye,Kim, Mi-Hyun,Lee, Jihoon,Park, Hyeung-Geun

, p. 4030 - 4039 (2013)

A new asymmetric synthetic method to prepare α,α- dialkylmalonates for the construction of a quaternary carbon center via phase-transfer catalytic (PTC) alkylation has been developed. Enantioselective α-alkylation of 2-methylbenzyl tert-butyl α-methylmalonates under phase-transfer catalytic conditions in the presence of (S,S)-3,4,5- trifluorophenyl-NAS bromide (10) afforded the corresponding α,α- dialkylmalonates in high chemical (up to 99%) and optical yields (up to 91% ee), which were selectively hydrolyzed to malonic monoacids under alkali basic conditions for conversion to versatile chiral intermediates. The Royal Society of Chemistry 2013.

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