144060-52-6

Basic information

• Product Name: 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid
• Synonyms: 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid
• CAS NO: 144060-52-6
• Molecular Formula: C₁₅H₁₄N₂O₃S
• Molecular Weight: 302.34826
• Mol File: 144060-52-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid(144060-52-6)
• EPA Substance Registry System: 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid(144060-52-6)

Safety Data

• Hazardous Substances Data: 144060-52-6(Hazardous Substances Data)

Usage

Uses

Febuxostat Isopropyl Isomer is an impurity of Febuxostat (F229000) which is a xanthine oxidase/xanthine dehydrogenase inhibitor.

Upstream product

• 144060-84-4 ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methyl-5-thiazolecarboxylate 

Relevant articles and documents

2-arylthiazole derivatives and pharmaceutical composition thereof

Pharmaceutical compositions for treating gout or hyperuricemia and containing a new categorized compound, i.e. 2-arylthiazole derivatives, as an active ingredient, are provided. The 2-arylthiazole derivatives in the present invention are represented by the following formula (I): STR1 wherein Ar is an unsubstituted or substituted pyridyl, thienyl, furyl, naphthyl or phenyl group; X is a hydrogen atom, alkyl group or carboxyl group which may be protected, and Y is a hydrogen atom, alkyl group, or a hydroxyl or carbonyl group which may be protected. Furthermore, novel compounds included in the 2-arylthiazole derivatives and pharmaceutically acceptable salts thereof are provided.