144060-84-4 Usage
Uses
Used in Pharmaceutical Industry:
Ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methyl-5-thiazolecarboxylate is used as an intermediate for the synthesis of Febuxostat Isopropyl Isomer (F229045). ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methyl-5-thiazolecarboxylate is an impurity of Febuxostat (F229000), which is a xanthine oxidase/xanthine dehydrogenase inhibitor. Febuxostat is a medication used to treat gout and hyperuricemia by reducing uric acid levels in the body. The use of this intermediate in the synthesis process is crucial for the development and production of effective treatments for these conditions.
Used in Chemical Research:
Due to its unique structure and functional groups, ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methyl-5-thiazolecarboxylate may also be used in chemical research for the development of new compounds and materials. Its reactivity and potential to form various derivatives make it a valuable candidate for exploring new chemical reactions and applications in different fields, such as materials science, agrochemistry, and environmental chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 144060-84-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,0,6 and 0 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 144060-84:
(8*1)+(7*4)+(6*4)+(5*0)+(4*6)+(3*0)+(2*8)+(1*4)=104
104 % 10 = 4
So 144060-84-4 is a valid CAS Registry Number.
144060-84-4Relevant academic research and scientific papers
2-arylthiazole derivatives and pharmaceutical composition thereof
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, (2008/06/13)
Pharmaceutical compositions for treating gout or hyperuricemia and containing a new categorized compound, i.e. 2-arylthiazole derivatives, as an active ingredient, are provided. The 2-arylthiazole derivatives in the present invention are represented by the following formula (I): STR1 wherein Ar is an unsubstituted or substituted pyridyl, thienyl, furyl, naphthyl or phenyl group; X is a hydrogen atom, alkyl group or carboxyl group which may be protected, and Y is a hydrogen atom, alkyl group, or a hydroxyl or carbonyl group which may be protected. Furthermore, novel compounds included in the 2-arylthiazole derivatives and pharmaceutically acceptable salts thereof are provided.
